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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A large cross-sectional study of children attending a health care center serving the largest community of Native Hawaiians (NH) in Hawaii showed a very high prevalence of overweight. This was especially pronounced in NH and Samoan children. The cause, significance and consequence of this high overweight prevalence, however, is unclear. Children with a high body mass index (BMI) percentile for age are at high risk for adult obesity and obesity related illness. However, because there are no body composition studies on Samoan or NH children defining the degree of excess adiposity at high BMI, it is not known if their risk is similar. A study examining the relationship between body fat percent (BF%) and BMI will help define the Pacific Island (PI) children at risk for obesity, especially those who are overweight. Studies have reported that Polynesian adults are leaner at a given BMI than Caucasians suggesting that obesity risk may be different. The overall aim of this study is to assess the feasibility of conducting a large body composition study on children of different PI ethnicities. The specific aims are 1) To examine the relationship between fat free mass (FFM) and BF% for a given BMI in Samoan, NH, Filipino and Caucasian children, 2) To develop mechanisms for estimating enrollment, creating community partnerships and recruiting participants, 3) To assess the effect size needed to assess FFM and BF% in a subsequent larger study. The study will be a cross sectional study on healthy NH, Samoan, Filipino and Caucasian children, 5 to 9.9 years of age. Participants will be recruited from the Waianae community of Oahu, home to a large Samoan community and the largest NH community. Fat free mass will be determined using foot-to-foot bioelectrical impedance analysis and the relationship between FFM, %BF and BMI examined.
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METABOLIC SYNDROME
  • 批准号:
    7960449
  • 项目类别:
  • 资助金额:
    $9.97万
  • 财政年份:
    2009
  • 负责人:
    MAY OKIHIRO
  • 依托单位:
BODY COMPOSITION
  • 批准号:
    7609606
  • 项目类别:
  • 资助金额:
    $1.57万
  • 财政年份:
    2007
  • 负责人:
    MAY OKIHIRO
  • 依托单位:
BODY COMPOSITION
  • 批准号:
    7380983
  • 项目类别:
  • 资助金额:
    $5.31万
  • 财政年份:
    2006
  • 负责人:
    MAY OKIHIRO
  • 依托单位:
BMI AND BP TRENDS IN CHILDREN
  • 批准号:
    7169049
  • 项目类别:
  • 资助金额:
    $0.92万
  • 财政年份:
    2005
  • 负责人:
    MAY OKIHIRO
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: