INBRE: USC: ENHANCEMENT OF BIOENGINEERING PROGRAM AT USC

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。南卡罗来纳大学(USC)将与克莱姆森大学(CU)和南卡罗来纳医科大学(MUSC)合作，发起一项以再生医学为广泛主题的合作研究计划。南加州大学的重点将是发育生物学和组织工程；克莱姆森大学的重点将是生物材料和生物支架；而南加州大学的重点将是干细胞生物学的应用。南加州大学的项目是医学院和工程与信息技术学院的联合努力。它将强调应用工程学的定量数学分析、建模和模拟技术来研究机械力(拉伸、应变、压力)对组织发育、形态和功能的影响，重点是心血管系统。南加州大学-INBRE计划将有三个主要目标：1)发展目标，初级教师；招聘跨学科生物工程教师；以及向以本科生为主的机构拓展。我们选择了四名初级教员在良好的指导下进行密集的专业发展；我们还建议招聘五名初级教员，INBRE项目每年一名，我们的医学院三名，我们的工程与信息技术学院两名。这些教师由一个大学间搜索委员会招聘，将加强工程师和生物医学科学家之间的合作，并为启动生物工程本科生和研究生课程提供基础。面向以本科生为主的机构的外展计划将包括通过指导关系进行直接互动，建立本科生研究实习机会，赞助一年一度的全州生物工程研讨会，以及提供关于图像技术在生物医学研究中应用的资源、培训和研讨会。通过加强我们与合作机构和我们自己的学院之间的合作，我们将在南卡罗来纳大学开发一个强大的生物工程项目。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of South Carolina (USC) will collaborate with Clemson University (CU) and the Medical University of South Carolina (MUSC) to initiate an collaborative research initiative under the broad theme of regenerative medicine. The focus of USC will be on developmental biology and tissue engineering; the focus at Clemson will be on biomaterials and bioscaffolds; and the focus at MUSC will be on applications of stem cell biology. The USC program is a joint effort between the School of Medicine and the College of Engineering and Information Technology. It will emphasize the application of the quantitative mathematical analysis, modeling and simulation techniques of engineering to study of the effects of mechanical forces (stretch, strain, pressure) on tissue development, morphology and function, with emphasis on the cardiovascular system. The USC-INBRE program will feature three main objectives: 1) development of target, junior faculty; recruitment of interdisciplinary bioengineering faculty; and outreach to Predominately Undergraduate Institutions. We have selected four junior faculty for intensive professional development under good mentorship; we also propose to hire five junior faculty, one in each year of the INBRE program, three in our School of Medicine and two in our College of Engineering and Information Technology. These faculty, recruited by an intercollege search committee, will strengthen the collaborations between engineers and biomedical scientists and provide a foundation for launching undergraduate and graduate programs in bioengineering. Outreach programs to Predominately Undergraduate Institutions will include direct interaction through a mentoring relationship, establishment of undergraduate research internships, sponsorship of an annual statewide Bioengineering colloquium, and providing resources, training and workshops on the application of image technology in biomedical research. By strengthening our collaborations with partner institutions and between our own colleges, we will develop a strong bioengineering program at the University of South Carolina.