TRANSEPITHELIAL ION TRANSPORT & ITS REGULATION

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。该项目的目标是确定在泌尿生殖系统上皮细胞中双向溶质和液体运输的细胞和调控途径。输精管(DD)和肾脏集合管(CD)的节段表达溶质吸收和分泌的转运蛋白，并对神经体液调节剂作出反应，表明这些上皮细胞具有调节双向离子转运的能力。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of the project is to determine, in urogenital epithelia, the cellular and regulatory pathways for bidirectional solute and fluid transport. Segments of the ductus deferens (DD) and renal collecting ducts (CD) express transport proteins for both solute absorption and secretion, and respond to neurohumoral modulators, indicating that these epithelia have capacities for regulated bidirectional ion transport.