MODELING OF A CEMENTED TOTAL HIP ARTHROPLASTY

骨水泥全髋关节置换术的建模

• 批准号: 7381668
• 负责人: MAURICIO A SANCHEZ
• 金额: $ 2.39万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381668
• 关键词: MODELING; CEMENTED; TOTAL; HIP; ARTHROPLASTY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this project is to expand previous research in the use of Polymethyl methacrylate (PMMA) for bone replacement, augmentation, and spacing in orthopedic surgery. The strategy applied to this research is to conduct finite element analysis (FEA) and heat transfer modeling (HTM) for several case scenarios of femoral or total hip arthroplasty (THA). With more than 125,000 total hip arthroplasty procedures undertaken each year in the United States, in order to alleviate the symptoms of trauma or degeneration of the hip it, is very important to analyze this surgical procedure from an engineering point of view. Many THA procedures are still being done using PMMA as an agent to solidify the bone with the femoral stem component in which it is expected to alleviate symptoms for about 10-years in most cases. These PMMA bone cements generate considerable heat, reaching temperatures of over 115oC, between 300 and 800 seconds after mixing with a liquid chemical hardener. Also, depending upon the curing method, different hardening properties are attained. Based upon these characteristics, we plan to investigate both the heat/temperature and force/stress phenomena a cemented total hip arthroplasty undergoes using three-dimensional computer simulations of an average size femoral hip replacement.

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。该项目的目的是扩展先前在骨科手术中使用聚甲基丙烯酸甲酯（PMMA）进行骨置换，增强和间距的研究。本研究采用的策略是对股骨或全髋关节置换术（THA）的几种情况进行有限元分析（FEA）和传热建模（HTM）。在美国每年有超过125,000例全髋关节置换术，为了减轻创伤或髋关节退变的症状，从工程学的角度分析这种手术是非常重要的。许多全髋关节置入术仍在使用PMMA作为一种剂来固化带有股骨干成分的骨，在大多数情况下，它有望缓解症状约10年。这些PMMA骨水泥与液体化学硬化剂混合后，在300到800秒内产生相当大的热量，达到超过115摄氏度的温度。此外，根据固化方法的不同，可以获得不同的硬化性能。基于这些特征，我们计划使用平均尺寸股骨髋关节置换术的三维计算机模拟来研究骨水泥全髋关节置换术所经历的热/温度和力/应力现象。