DE PEDIATRIC COBRE: CELL SCIENCE CORE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。细胞科学核心对本中心所有五个项目的发展至关重要。该中心汇集了该系内所有可用的细胞和分子生物学资源，并提供特拉华大学和特拉华生物技术研究所提供的额外服务。细胞科学中心将为细胞生物学、蛋白质生物化学和分子生物学的准备和分析研究提供服务和资源。准备设施：该设施将提供一个集中的人员组织培养设施，用于制备匿名ebv不朽的淋巴母细胞样细胞系和人类受试者的成纤维细胞培养物，以及人类研究组织和样本的银行，并将维护其他不朽细胞系，并作为这些调用试剂的银行。分析设施：该设施将包括细胞生物学资源，蛋白质生物化学资源和分子生物学亚核心。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A Cell Science Core is critical to the development of all five of the projects in this Center. The Core brings together all of the cell and molecular biological resources available within the department, and provides access to additional services available at the University of Delaware and the Delaware Biotechnology Institute. The Cell Science Core will provide services and resources for preparative and analytical studies for cell biology, protein biochemistry and molecular biology. Preparative Facility: This facility will provide a centralized staffed tissue culture facility for preparation of anonymized EBV-immoralized lymphoblastoid cell lines and fibroblast cultures from human subjects and banking of human research tissues and samples, and will also maintain other immortalized cell lines and serve as a bank for these call-based reagents. Analytical Facility: This facility will consist of the Cell Biology Resource, Protein Biochemistry Resource and Molecular Biology subcores.