COBRE:OUHSC: IMAGE ACQUISITION & PRODUCTION CORE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。图像采集和生成模块。所有PJl的研究项目，以及一名常驻学者的研究项目，都涉及到该核心的使用。本模块的目的是提供高质量的最先进的仪器和专业知识，以获得光学，荧光和诺马斯基光学显微镜图像；以可检索的格式存档图像，提供形态计量学分析并制作出版质量的印刷品。该模块位于Dean McGee眼科研究所的地下室，占地600平方英尺。模块设备包括光学图像采集设备，与三个计算机工作站连接，用于图像存储、检索、分析和修改，以及用于嵌入、切片、组织化学和免疫化学染色的设备。该模块包括系统经理和组织学技术人员，他们将协助PJrs处理组织和制作图像，或在任何设备的操作中提供协助。图像采集和生产模块已经以组织处理的最大容量运行，所要求的组织学技术人员将使PJl的项目能够获得优先调度。该模块的服务是最劳动密集型的，将使PJl能够更快、更大量地获得数据，对其进行分析，并为手稿、海报或幻灯片演示制作出版质量的图像。该模块有潜力最大限度地提高每个PJl在视觉研究方面的生产力，从而加强他们成功竞争未来NIH R01资金的能力。这反过来不仅会增加俄克拉何马州视觉研究调查员的数量，还会提高研究的质量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Image Acquisition and Production Module. The research projects of all PJl's, and one of the Resident Scholars, involve the use of this core. The purpose of this module is to provide quality state of the art instrumentation and expertise to obtain microscopic images with light, fluorescent and Nomarski optics; to archive the images in a retrievable format, to provide for morphometric analysis and to produce publication quality prints. The Module comprises 600sq ft in the basement of the Dean McGee Eye Institute. The Module equipment consists of optical image acquisition devices interfaced with three computer work stations with internet access for image storage, retrieval, analysis and modification as well as equipment for embedding, sectioning, and histochemical and immunochemical staining. The module includes a Systems Manager and histology technicians who will assist the PJrs either in the processing of tissue and production of images, or by providing assistance in the operation of any of the equipment. The Image Acquisition and Production Module is already operating at maximum capacity for tissue processing and the histology technician requested will enable the PJl's projects to be receive priority scheduling. The services of this module are the most labor intensive and will enable the PJl's to obtain their data more rapidly, in greater quantity, to analyze it and to produce publication quality images for manuscripts, posters or Power Point presentations. This Module has the potential to maximize the productivity of each of the PJl's in vision research and thereby strengthen their ability to successfully compete for future NIH R01 funding. This in turn will increase not only the number of Vision Research Investigators in Oklahoma but also the quality of the research.