COBRE:OUHSC: IMAGE ACQUISITION & PRODUCTION CORE

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 图像采集和制作模块。所有PJL、ECI、试点研究人员、他们的导师、模块主任和PI的研究项目都涉及到这一核心的使用。该单元的目的是提供高质量的最先进的仪器和专业知识，以获得使用光、荧光和诺马尔斯基光学技术的显微图像；以可检索的格式存档图像，提供形态测量分析和制作出版质量的印刷品。这个模块有600平方英尺，位于Dean McGee眼科研究所的地下室。该模块设备包括光学图像采集设备，与三个可接入互联网的计算机工作站接口，用于图像存储、检索、分析和修改，以及包埋、切片和组织化学和免疫化学染色设备。该单元包括一名系统管理员和组织学技术员，他们将协助PJRS处理组织和制作图像，或协助操作任何设备。图像采集和制作模块已经在组织处理的最大能力下运行，所需的组织学技术员将使PJL的项目能够优先得到安排。这一模块的服务是劳动密集型的，将使PJL能够更快、更多地获得他们的数据，对其进行分析，并为手稿、海报或Power Point演示文稿制作出版质量的图像。这一模块有可能最大限度地提高每个PJL在视觉研究方面的生产率，从而增强他们成功竞争未来NIH R01资金的能力。这反过来将不仅增加俄克拉荷马州视觉研究调查人员的数量，而且还将提高研究的质量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Image Acquisition and Production Module. The research projects of all PJl's, ECIs, Pilot Researchers, their mentors, module directors and PI involve the use of this core. The purpose of this module is to provide quality state of the art instrumentation and expertise to obtain microscopic images with light, fluorescent and Nomarski optics; to archive the images in a retrievable format, to provide for morphometric analysis and to produce publication quality prints. The Module comprises 600sq ft in the basement of the Dean McGee Eye Institute. The Module equipment consists of optical image acquisition devices interfaced with three computer work stations with internet access for image storage, retrieval, analysis and modification as well as equipment for embedding, sectioning, and histochemical and immunochemical staining. The module includes a Systems Manager and histology technicians who will assist the PJrs either in the processing of tissue and production of images, or by providing assistance in the operation of any of the equipment. The Image Acquisition and Production Module is already operating at maximum capacity for tissue processing and the histology technician requested will enable the PJl's projects to be receive priority scheduling. The services of this module are the most labor intensive and will enable the PJl's to obtain their data more rapidly, in greater quantity, to analyze it and to produce publication quality images for manuscripts, posters or Power Point presentations. This Module has the potential to maximize the productivity of each of the PJl's in vision research and thereby strengthen their ability to successfully compete for future NIH R01 funding. This in turn will increase not only the number of Vision Research Investigators in Oklahoma but also the quality of the research.