Interpretation Modification Program for Social Phobia

社交恐惧症解释修正计划

• 批准号: 7494136
• 负责人: NADER AMIR
• 金额: $ 20.18万
• 依托单位: SAN DIEGO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-07 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7494136
• 关键词: Aftercare; Anxiety; Anxiety Disorders; Behavioral; Benign; Clinic; Clinical; Cognitive; Cognitive Science; Cognitive Therapy; Computer information processing; Data; Disease; Event; Feedback; Goals; High Prevalence; Individual; Intervention; Investigation; Laboratory Research; Measures; Mediating; Mental disorders; Modeling; Modification; Participant; Pathogenesis; Patient Representative; Patients; Placebos; Pliability; Population; Positioning Attribute; Prevalence; Procedures; Psychopathology; Research; Role; Score; Services; Social Phobia; Symptoms; Techniques; Testing; Thinking; Translating; Treatment Efficacy; Treatment outcome; base; computer program; computerized; cost; design; functional disability; improved; novel; programs; randomized placebo controlled trial; social

DESCRIPTION (provided by applicant): Social phobia is characterized by severe social anxiety leading to functional impairment (Schneider et al., 1992). Despite its high prevalence (13%, Kessler et al., 1994) over 30% of individuals with social anxiety who need treatment do not receive treatment (Olfson, et al., 2000) and 40% of individuals who present for treatment do not respond (39%, Heimberg, et al., 1998; 42%, Liebowitz et al., 2005). Thus, there is a clear need to develop highly effective and efficient treatments for GSP. Reducing negative interpretation of social events is an efficacious treatment for SP because:1) benign interpretations is associated with improvement in social anxiety after treatment (e.g., Franklin, Huppert, Langner, Leiberg, & Foa, 2005), 2) negative interpretations are implicated in the pathogenesis of SP (e.g., Rapee & Heimberg, 1997), 3) SPs have more negative interpretations of social events than non-anxious controls and individuals with other anxiety disorders (e.g., Amir et al, 1998), and 4) this bias ameliorates after successful treatment (e.g., Stopa & Clark, 2000). Therefore, changing negative interpretations is an efficacious treatment for SP, and current cognitive- behavioral therapies use cognitive restructuring (CR) to target negative interpretations and replace them with more benign interpretations (Heimberg, et al., 1998). The goal of the current application is to test a new computerized treatment for SP that is designed to change negative interpretations. We chose a computerized intervention to increase efficiency and ease of delivery. We chose to test this intervention in GSP because interpretation bias is especially relevant to this clinical population. The long-term goal of this project is to improve service delivery using a widely available and economical intervention for GSP. More specifically, we will test three hypotheses in this application: 1) Individuals with GSP completing the Interpretation Modification Program (IMP) will show a reduction in their negative interpretation, 2) Participants in the IMP will show a decrease in their social anxiety symptoms, 3) Change in social anxiety symptoms will be mediated by the change in interpretation scores, suggesting that interpretation change reduced social anxiety symptoms. Pilot data (n=34) suggest that this intervention is efficacious. Thus, we aim to develop further and validate this highly efficient treatment for changing interpretations as a cost-effective treatment for patients with social phobia. Social phobia has high prevalence (13%, Kessler et al., 1994) and leads to functional impairment (Schneider et al., 1992). However, over 30% of individuals with social phobia do not receive treatment (Olfson, et al., 2000) and 40% of individuals who present for treatment do not respond (39%, Heimberg, et al., 1998; 42%, Liebowitz et al., 2005). The goal of this project is develop and test a new computerized treatment for social phobia.

描述(申请人提供)：社交恐惧症的特征是严重的社交焦虑导致功能障碍(Schneider等人，1992)。尽管社交焦虑症的发病率很高(13%，Kessler等人，1994年)，但超过30%的需要治疗的社交焦虑症患者没有接受治疗(Olfson等人，2000年)，40%的出席治疗的人没有反应(39%，Heimberg等人，1998年；42%，Liebowitz等人，2005年)。因此，显然有必要开发高效、高效的GSP治疗方法。减少对社交事件的负面解读是治疗SP的有效方法，因为：1)良性解读与治疗后社交焦虑的改善有关(例如Franklin，Huppert，Langner，Leiberg，&Foa，2005)，2)负面解读与SP的发病机制有关(例如，Rapee&Heimberg，1997)，3)SP对社交事件的负面解读比非焦虑对照组和其他焦虑症患者更多(例如，Amir et al，1998)，以及4)这种偏见在成功治疗后得到改善(例如，Stopa&Clark，2000)。因此，改变消极解释是治疗SP的一种有效方法，目前的认知-行为疗法使用认知重构(CR)来针对消极解释，并用更良性的解释来取代它们(Heimberg等人，1998)。目前应用程序的目标是测试一种新的计算机治疗SP的方法，该方法旨在改变负面解释。我们选择了电脑干预，以提高效率和交付的简便性。我们选择在GSP中测试这种干预，因为解释偏差与这一临床人群特别相关。该项目的长期目标是利用广泛可用和经济的普惠制干预措施改善服务提供。更具体地说，我们将检验三个假设：1)完成口译修改计划(IMP)的GSP个体的负面口译将会减少，2)IMP参与者的社交焦虑症状将会减少，3)社交焦虑症状的变化将通过口译分数的变化来调节，这表明口译改变会减少社交焦虑症状。试点数据(n=34)表明，这种干预措施是有效的。因此，我们的目标是进一步开发和验证这种改变解释的高效治疗方法，作为治疗社交恐惧症患者的经济有效的治疗方法。社交恐惧症有很高的流行率(13%，Kessler等人，1994年)，并导致功能障碍(Schneider等人，1992)。然而，超过30%的社交恐惧症患者没有接受治疗(Olfson等人，2000年)，40%的出席治疗的人没有反应(39%，Heimberg等人，1998年；42%，Liebowitz等人，2005年)。这个项目的目标是开发和测试一种新的社交恐惧症的计算机化治疗方法。