Propagating the Uniform Research Integrity Climate Assessment (U-RICA)

描述(由申请人提供)：在试图促进科学研究的完整性方面，大多数研究组织(如果不是所有的研究组织)都倾向于内部自律的方法，而不是倾向于遵守外部强加的任务的方法。然而，自律在这方面的效果如何，以及在不同大学之间的差异性，仍然是一个悬而未决的问题。适当地确定教育干预措施或组织变革举措的目标，以促进研究的完整性，要求各组织有能力收集可靠的数据，以确定基准条件，评估需要改进的领域，并随后评估具体举措的影响。作为大多数生物医学研究的中心，由国家卫生研究院(NIH)、学术健康中心提供外部资金。(AHC)研究诚信的氛围尤为突出。建立有效、可靠和标准化的自我监测工具是促进其有效内部自我调节能力的关键一步。目前的NIH临床和翻译科学奖(CTSA)计划本身就是一项变革倡议，旨在加速将基础和临床研究成果转化为实际的健康益处，为开始实施此类标准化测量提供了及时的机会和合理的场所。这个R21项目的双重目标是，1)开发一个工具--统一研究完整性气候评估工具(U-RICA)--这将使AHC能够收集可靠、有效和可操作的数据，以促进内部讨论和促进研究完整性的倡议，以及2)为在CTSA联盟框架内采用和传播这一工具奠定基础。评估和建立U-RICA的心理测量学特性(内部和重测信度；结构和预测效度)将通过在美国75所顶尖研究型大学中挑选10-15所AHC的学术研究人员的大样本、嵌套和随机抽样来完成。为了促进通过U-RICA，我们从目前持有CTSA奖的几所先锋大学的伦理核心中安排了一个意见领袖小组。通过季度会议和与这些领导人的讨论，我们将进行可行性分析，以确定机会、利益相关者和可能的战略，以及在CTSA联盟中成功推广使用U-RICA工具所面临的已知风险、潜在障碍和威胁。 该项目将提供具体的材料和机制，帮助学术卫生中心培育和维护支持研究诚信的氛围和文化。通过这样做，该项目将有助于确保在这些环境中进行的医学和公共卫生研究具有最高的质量和完整性，从而使公众健康受益。

DESCRIPTION (provided by applicant): In attempting to promote the integrity of scientific research, most, if not all research organizations would prefer an internal, self-regulatory approach over one favoring compliance with externally imposed mandates. How well self-regulation works for this purpose, however, and its variability across universities, remain open questions. Appropriate targeting of educational interventions or organizational change initiatives to promote research integrity require that organizations have the ability to collect reliable data to benchmark baseline conditions, to assess areas needing improvement, and to subsequently assess the impact of specific initiatives. As the locus of the majority of the biomedical research conducted with extramural funding from the National Institutes of Health (NIH), Academic Health Centers. (AHCs) research integrity climates are particularly salient. The creation of valid, reliable, and standardized tools for self-monitoring on the part of AHCs is a vital step in facilitating their capacity for effective internal self-regulation. The current NIH Clinical and Translational Science Awards (CTSAs) program, itself a change initiative to hasten the translation of basic and clinical research findings into practical health benefits, provides a timely opportunity and logical venue in which to begin implementing such standardized measurement. The dual goals of this R21 project are, 1) to develop a tool the Uniform Research Integrity Climate Assessment instrument (U-RICA) - that would allow AHCs to collect reliable, valid, and actionable data to stimulate internal discussions and initiatives to promote research integrity, and 2) to lay the groundwork for the adoption and dissemination of this tool within the framework of the CTSA Consortium. Assessing and establishing the psychometric properties (internal & test-retest reliability; construct and predictive validity) of the U-RICA will be accomplished by fielding the instrument in a large, nested, random sample of academic researchers employed in 10-15 AHCs selected from among the top 75 U.S. research universities. To facilitate the adoption of the U-RICA, we have empanelled a group of opinion leaders from within the ethics cores of several vanguard universities currently holding CTSA awards. Through quarterly meetings and discussions with these leaders, we will conduct a feasibility analysis to identify opportunities, stakeholders, and possible strategies as well as perceived risks, potential hurdles, and threats facing the success of propagating use of the U-RICA tool in the CTSA Consortium. This project will provide concrete materials and mechanisms to help academic health centers foster and maintain climates and cultures supportive of research integrity. By so doing, this project will benefit the public health by helping to ensure that medical and public health research conducted in these settings is of the highest quality and integrity.