Headstrong Intervention for Recurrent Pediatric Headache

顽固干预治疗复发性小儿头痛

• 批准号: 7586519
• 负责人: MICHAEL Andrew RAPOFF
• 金额: $ 7.35万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7586519
• 关键词: Address; Affect; Age; Age-Years; American; Applications Grants; CD-ROM; Caring; Child; Childhood; Chronic Daily Headaches; Cognitive Therapy; Computers; Condition; Control Groups; Daily; Data; Diagnosis; Education; Effectiveness; End Point; Enrollment; Etiology; Family health status; Frequencies; Goals; Headache; Headache Syndrome; Home environment; Intervention; Learning; Measures; Medical; Migraine; Moods; Muscle Contraction; NIH Program Announcements; Outcome; Outcome Study; Pain; Pain management; Patients; Prevalence; Quality of life; Randomized; Randomized Controlled Clinical Trials; Recurrence; Reporting; Research; Standards of Weights and Measures; Stress; Stressful Event; Syndrome; Treatment Protocols; Work; base; biobehavior; care systems; chronic pain; cost; diaries; disability; follow-up; functional disability; health related quality of life; innovation; programs; psychological distress; response

Recurrent pediatric headache is a chronic pain syndrome affecting more than two million American children and often resulting in significant functional disability and debilitation. Moreover, this syndrome represents a substantial cost to the patient's family and the health care system. The goal of the present study is to evaluate the efficacy of a new cost-effective approach to the treatment of recurrent pediatric headache that allows children to learn how to self-manage their headaches via a CD-ROM program (called "HeadstrongTM"). This grant proposal is being submitted in response to PA-01-115, which called for research seeking to identify and refine innovative and effective treament strategies for specific pain conditions. A randomized trial will be used to evaluate the effectiveness of the Headstrong TM intervention. One-hundred and eight (108) pediatric patients, ages 7-12 years, with a diagnosed recurrent migraine, muscle-contraction, or chronic daily headache syndrome will be enrolled in the study. After enrollment, each patient's baseline headache frequency, duration, and intensity will be assesed for one month using headache diaries. During this one-month baseline period, we will also collect data_to examine headache-related disability and health- related quality of life. After baseline, patients will be randomly assigned to the standard medical care plus Headstrong TM intervention or the standard medical care plus Education condition (also a CD-ROM program with information about recurrent headaches, such as types, etiology, and triggers). Both groups will work through modules in their respective programs over the co._se of one month. Dependent measures will then continue to be collected at one-month post-treatment and three-, six-, and twelve-month post-treatment follow-up. The primary study outcome will be headache_ frequency, duration, and intensity as measured by daily headache diaries. Secondary endpoints will include ,headache-related disability outcomes and quality of life. _ .....

儿童复发性头痛是一种慢性疼痛综合征，影响着200多万美国儿童 并经常导致严重的功能残疾和虚弱。此外，这种综合征代表着一种 给患者家庭和医疗保健系统带来了巨大的成本。本研究的目标是评估 一种新的具有成本效益的方法治疗复发性儿童头痛的疗效 儿童学习如何通过CD-ROM程序(称为“Headstrong TM”)自我管理他们的头痛。这 正在提交拨款提案，以响应PA-01-115，该提案呼吁进行研究，以确定和 针对具体的疼痛情况，改进创新和有效的治疗策略。 一项随机试验将用于评估Headstrong TM干预的有效性。一百美元 以及8(108)名7-12岁的儿科患者，被诊断为反复发作的偏头痛、肌肉收缩、 或者慢性日常头痛综合征将被纳入研究。登记后，每个患者的基线 头痛的频率、持续时间和强度将使用头痛日记进行一个月的评估。在.期间 在这一个月的基准期内，我们还将收集数据--以检查与头痛相关的残疾和健康- 相关的生活质量。基线后，患者将被随机分配到标准医疗护理加 Headstrong TM干预或标准医疗加教育条件(也是CD-ROM计划 关于反复头痛的信息，如类型、病因和触发因素)。两个小组都将发挥作用 在一个月的时间里通过各自程序中的模块。然后，依赖的措施将 继续在治疗后一个月以及治疗后三个月、六个月和十二个月收集 后续行动。主要研究结果将是头痛的频率、持续时间和强度，由 每天的头痛日记。次要终点将包括头痛相关的残疾结果和质量 生活。_……

项目成果

Headstrong intervention for pediatric migraine headache: a randomized clinical trial.

• DOI: 10.1186/1129-2377-15-12
• 发表时间: 2014-02-28
• 期刊: The journal of headache and pain
• 作者: Rapoff MA;Connelly M;Bickel JL;Powers SW;Hershey AD;Allen JR;Karlson CW;Litzenburg CC;Belmont JM
• 通讯作者: Belmont JM