Jointstrong intervention for juvenile arthritis

幼年关节炎的联合强干预

基本信息

批准号：
8038555
负责人：
MICHAEL Andrew RAPOFF
金额：
$ 8.23万
依托单位：
UNIVERSITY OF KANSAS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-04-01 至 2011-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8038555
关键词：
12 year old Address Adolescent Adult Affect Aftercare Age Behavioral CD-ROM Caring Child Childhood Chronic Chronic Childhood Arthritis Chronic Headaches Clinical Trials Cognitive Cognitive Therapy Computers Control Groups Critiques Data Development Diagnosis Disease Family Fatigue Frequencies Funding Gender Generic Drugs Grant Health Care Costs Hour Internet Intervention Kansas Measures Medical Medical center Minimal Contact Treatment Moods National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Neurological Disorders and Stroke Pain Pain management Participant Patients Pharmacological Treatment Pilot Projects Quality of life Randomized Randomized Clinical Trials Randomized Controlled Trials Recurrent pain Relative (related person)Reporting Research Priority Rheumatism Stress Stressful Event Symptoms Technology Testing Universities Waiting Lists base biopsychosocial chronic pain coping cost diaries disability follow-up functional disability improved innovation programs response

项目摘要

DESCRIPTION (provided by applicant): This R21 pilot study addresses behavioral and biopsychosocial research priorities of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to conduct studies of non-pharmacological interventions, including technology-based interventions, for chronic symptoms such as pain. Chronic or recurrent pain is central feature of juvenile arthritis (JA). About 25 to 30 percent report moderate to severe pain and the great majority of children with JA report at least some pain lasting from 30 minutes to 24 hours a day, with a mean of 4.3 hours per day. In addition, long-term follow up shows that the adults who were diagnosed with JA report significantly greater pain, fatigue, and disability relative to gender-matched healthy cases. Thus, for many children with JA pain is a significant problem that persists into adulthood and is associated with significant disability. And, in spite of advancements in pharmacological treatments foonic childhood pain. The primary aim of this application is to develop and pilot test "Jointstrong," an adjunctive computer-based cognitive-behavioral intervention for pain in children with JA. This pilot study will randomly assign 36 children, 8 to 12 years with JA to the Jointstrong program or a wait-list control group. Daily diary measures of pain intensity, duration, and frequency, mood and stress, as well as quality of life measures will be taken during two-week intervals at baseline, immediate post-treatment, and 3-month follow-up. Hypotheses are that children who receive the Jointstrong in combination with standard medical care will demonstrate greater improvement on the pain, mood and stress, and quality of life measures than children in a standard medical care (wait-list) control group. If this pilot study is successful, a larger R01 clinical trial will be proposed to further validate the Jointstrong program. PROJECT NARRATIVE: The development of computer-based adjunctive pain management programs for children with chronic pain, such as JA, can be cost-effective and easily disseminated to patients and families via CD-ROM programs or on the Web. These programs can also reduce health care costs and functional disability and improve the quality of life for children with chronic or recurrent pain.

描述（由申请人提供）：这项R21试点研究介绍了国家关节炎和肌肉骨骼和皮肤病研究所（NIAMS）的行为和生物心理社会研究优先事项（NIAMS），以进行非药理学干预措施，包括基于技术的干预措施，以解决诸如慢性疼痛之类的慢性症状。慢性或复发性疼痛是青少年关节炎（JA）的核心特征。大约25％至30％的人报告中度至重度疼痛，而患有JA的绝大多数儿童报告至少每天30分钟至24小时持续一些疼痛，平均每天4.3小时。此外，长期的随访表明，被诊断出患有JA的成年人报告的疼痛，疲劳和残疾相对于性别匹配的健康病例，疼痛，疲劳和残疾。因此，对于许多患有JA疼痛的儿童来说，这是一个重大的问题，它持续到成年，并且与严重的残疾有关。而且，尽管药理治疗方面的进步，但儿童疼痛。该应用程序的主要目的是开发和进行试验测试“ intrigstrong”，这是一种基于计算机的辅助性认知行为干预JA儿童的疼痛。这项试点研究将随机分配36名儿童，与JA一起将36个儿童分配给联合弦计划或等待名单对照组。每日日记的疼痛强度，持续时间，频率，情绪和压力以及生活质量措施的措施将在基线，立即治疗和3个月的随访期间进行两周的时间。假设是，与标准医疗相比，与标准的医疗服务相比，与标准医疗的疼痛，情绪和压力和生活质量措施相比，接受关节体的儿童将表现出更大的改善。如果这项试点研究成功，将提出更大的R01临床试验，以进一步验证关节弦计划。项目叙述：针对患有慢性疼痛的儿童（例如JA）的基于计算机的辅助疼痛管理计划可以具有成本效益，并且可以通过CD-ROM程序或网络上的患者和家庭轻松地传播给患者和家庭。这些计划还可以降低医疗保健成本和功能障碍，并改善慢性或经常性疼痛儿童的生活质量。