Jointstrong intervention for juvenile arthritis

幼年关节炎的联合强干预

• 批准号: 7599595
• 负责人: MICHAEL Andrew RAPOFF
• 金额: $ 16.17万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7599595
• 关键词: 12 year old; Address; Adolescent; Adult; Affect; Aftercare; Age; Behavioral; CD-ROM; Caring; Child; Childhood; Chronic; Chronic Childhood Arthritis; Chronic Headaches; Clinical Trials; Cognitive; Computers; Control Groups; Critiques; Data; Development; Diagnosis; Disease; Family; Fatigue; Frequencies; Funding; Gender; Generic Drugs; Grant; Health Care Costs; Hour; Internet; Intervention; Kansas; Measures; Medical; Medical center; Minimal Contact Treatment; Moods; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; Pain; Pain management; Participant; Patients; Pharmacological Treatment; Pilot Projects; Quality of life; Randomized; Randomized Clinical Trials; Randomized Controlled Trials; Recurrent pain; Relative (related person); Reporting; Research Priority; Rheumatism; Stress; Stressful Event; Symptoms; Technology; Testing; Universities; Waiting Lists; base; biopsychosocial; chronic pain; cognitive behavior therapy; coping; cost; diaries; disability; follow-up; functional disability; improved; innovation; programs; response

DESCRIPTION (provided by applicant): This R21 pilot study addresses behavioral and biopsychosocial research priorities of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to conduct studies of non-pharmacological interventions, including technology-based interventions, for chronic symptoms such as pain. Chronic or recurrent pain is central feature of juvenile arthritis (JA). About 25 to 30 percent report moderate to severe pain and the great majority of children with JA report at least some pain lasting from 30 minutes to 24 hours a day, with a mean of 4.3 hours per day. In addition, long-term follow up shows that the adults who were diagnosed with JA report significantly greater pain, fatigue, and disability relative to gender-matched healthy cases. Thus, for many children with JA pain is a significant problem that persists into adulthood and is associated with significant disability. And, in spite of advancements in pharmacological treatments foonic childhood pain. The primary aim of this application is to develop and pilot test "Jointstrong," an adjunctive computer-based cognitive-behavioral intervention for pain in children with JA. This pilot study will randomly assign 36 children, 8 to 12 years with JA to the Jointstrong program or a wait-list control group. Daily diary measures of pain intensity, duration, and frequency, mood and stress, as well as quality of life measures will be taken during two-week intervals at baseline, immediate post-treatment, and 3-month follow-up. Hypotheses are that children who receive the Jointstrong in combination with standard medical care will demonstrate greater improvement on the pain, mood and stress, and quality of life measures than children in a standard medical care (wait-list) control group. If this pilot study is successful, a larger R01 clinical trial will be proposed to further validate the Jointstrong program. PROJECT NARRATIVE: The development of computer-based adjunctive pain management programs for children with chronic pain, such as JA, can be cost-effective and easily disseminated to patients and families via CD-ROM programs or on the Web. These programs can also reduce health care costs and functional disability and improve the quality of life for children with chronic or recurrent pain.

描述(由申请人提供)：这项R21试点研究旨在解决国家关节炎和肌肉骨骼及皮肤病研究所(NIAMS)的行为和生物心理社会研究重点，以进行针对疼痛等慢性症状的非药物干预研究，包括基于技术的干预。慢性或复发性疼痛是青少年关节炎(JA)的主要特征。大约25%到30%的儿童报告说有中度到重度的疼痛，绝大多数患有JA的儿童报告说至少有一些疼痛每天持续30分钟到24小时，平均每天4.3小时。此外，长期随访显示，与性别匹配的健康病例相比，被诊断为JA的成年人报告的疼痛、疲劳和残疾明显更严重。因此，对于许多患有JA的儿童来说，疼痛是一个持续到成年的重大问题，并与严重的残疾有关。而且，尽管在药物治疗方面取得了进步，但儿童时期的疼痛。该应用程序的主要目的是开发和试点测试“Jointstrong”，这是一种辅助的基于计算机的认知行为干预，用于治疗患有JA的儿童的疼痛。这项试点研究将36名8至12岁患有JA的儿童随机分配到Jointstrong计划或等待名单控制组。每日日记测量疼痛强度、持续时间和频率、情绪和压力，以及生活质量测量，在基线、治疗后立即和3个月的随访期间进行两周间隔。假设是，在标准医疗护理的同时接受Jointstrong治疗的儿童将比标准医疗护理(等待名单)对照组的儿童在疼痛、情绪和压力以及生活质量方面表现出更大的改善。如果这项试点研究成功，将提议进行更大规模的R01临床试验，以进一步验证Jointstrong计划。项目简介：为患有慢性疼痛的儿童开发基于计算机的辅助疼痛管理程序，如JA，可以具有成本效益，并可通过CD-ROM程序或在Web上轻松传播给患者和家庭。这些计划还可以降低医疗保健成本和功能残疾，并提高慢性或复发性疼痛儿童的生活质量。