EXERCISE TRAINING ON BONE MINERAL DENSITY IN FRAIL OLDER WOMEN AND MEN

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。SIR-前瞻性研究表明，随着年龄的增长，骨丢失加速，导致骨矿物质密度（BMD）显着降低。由于体力活动为骨骼健康提供了机械刺激，老年人的低BMD可能部分归因于废用性萎缩。一些随机对照试验（RCT）发现，运动可以增加老年人的BMD，但局限性在于没有包括老年人，身体虚弱的人。本研究的目的是评估多成分运动计划与低强度家庭运动相比对老年体弱个体骨密度的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. SIR-Prospective studies suggest that bone loss accelerates with advancing age, leading to markedly decreased bone mineral density (BMD). Because physical activity provides the mechanical stimulus for bone health, low BMD in old age may be due, in part, to disuse atrophy. Some randomized controlled trials (RCT) have found that exercise increases BMD in older adults, but a limitation is that older, physically frail individuals were not included. The aim of this study was to evaluate the effects of a multi-component exercise programme, compared with low intensity home exercise, on BMD in older frail individua