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Heparin Induced Thrombocytopenia (HIT): further characterization of disease mechanism will improve patient treatment

Heparin Induced Thrombocytopenia (HIT): further characterization of disease mechanism will improve patient treatment
肝素诱导血小板减少症(HIT):疾病机制的进一步表征将改善患者治疗
批准号:
nhmrc : 1109745
负责人:
Prof Beng Chong
金额:
$31.3万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

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中文摘要
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英文摘要
Thrombus formation occurs as a side effect of heparin treatment in many patients. This condition is called Heparin Induced Thrombocytopenia (HIT). The clots may be stabilised by secretions from cells called neutrophils. In this project we will study this possibility using a mouse model of HIT and will explore therapeutic approaches to inhibit clot stabilisation.
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Novel Mechanisms, Molecular Targets and Therapies in Cardiovascular Disease
  • 批准号:
    nhmrc : 1052616
  • 项目类别:
    Program Grants
  • 资助金额:
    $596.79万
  • 财政年份:
    2014
  • 负责人:
    Prof Beng Chong
  • 依托单位:
Mechanisms and Therapies in Cardiovascular Disease
  • 批准号:
    nhmrc : GNT1052616
  • 项目类别:
    Programs
  • 资助金额:
    $836.07万
  • 财政年份:
    2014
  • 负责人:
    Prof Beng Chong
  • 依托单位:
Heparin-induced thrombocytopenia and thrombosis: Better understanding of pathogenesis and improving diagnosis and treatment
  • 批准号:
    nhmrc : 1028803
  • 项目类别:
    Project Grants
  • 资助金额:
    $43.55万
  • 财政年份:
    2012
  • 负责人:
    Prof Beng Chong
  • 依托单位:
Drug-induced immune thrombocytopenia: Understanding the disease mechanisms is the key to better treatment
  • 批准号:
    nhmrc : 1012409
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $33.98万
  • 财政年份:
    2011
  • 负责人:
    Prof Beng Chong
  • 依托单位:
国内基金
海外基金
炎性反应中巨噬细胞激活诱导死亡(activation-induced cell death,AICD)的机理研究
  • 批准号:
    30330260
  • 项目类别:
    重点项目
  • 资助金额:
    105.0万元
  • 批准年份:
    2003
  • 负责人:
    顾军
  • 依托单位: