Disposable Respiratory Flow Measurement Device
一次性呼吸流量测量装置
基本信息
- 批准号:7539571
- 负责人:
- 金额:$ 11.97万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-09-15 至 2009-03-14
- 项目状态:已结题
- 来源:
- 关键词:Accelerated PhaseAccountingAdultAffectAirAmbulatory MonitoringAnesthesia proceduresAppendixApplications GrantsAreaBaltimoreBenchmarkingBreathingCannulasChildChildhoodChronic Obstructive Airway DiseaseClinicClinicalClinical MedicineCoinConsultCritiquesDataDetectionDevelopmentDevicesDiagnosisDiagnosticDiagnostic ProcedureDisciplineElectronicsEnvironmentEnvironmental air flowEventExhalationFaceFailureFeedbackFrequenciesFundingFutureGoalsGoldGrantHome environmentHospitalsHourHumanHumidityHypercapnic respiratory failureIndustryKnowledgeLaboratoriesLongitudinal StudiesManufacturer NameMarketingMasksMeasurementMeasuresMechanicsMedicalMedicineMethodsMirageModificationMonitorMorphologic artifactsMotionMouth BreathingNoseNumbersOSAOralPatient CarePatient MonitoringPatientsPatternPerformancePhasePhysiologicalPlasticsPlayPolysomnographyPopulationPositioning AttributeProceduresProductionPublic HealthPublished CommentPulmonologyPurposeRangeRecommendationRelative (related person)ReproducibilityResearchResearch PersonnelResistanceRespirationScienceSignal TransductionSleepSleep DisordersStandards of Weights and MeasuresSystemTechniquesTechnologyTelephoneTemperatureTest ResultTestingTidal VolumeTimeTooth structureTranslatingTubeValidationVariantWireless TechnologyWorkbasecommercializationcomputerized data processingconceptcostdaydesignface maskimprovedinnovationmetermilliliterperformance testspressureprototyperesearch and developmentrespiratoryresponsesensorsizesuccesstooltransmission processusabilityvalidation studies
项目摘要
DESCRIPTION (provided by applicant): The overall goal of this project is to develop, formally benchmark and validate a new flow sensor that will accurately quantify varying degrees of ventilation in pediatric and adult patient populations. The flow sensor is a simple, non-contact, disposable part that provides quantitative measurement of respiratory activity, even in the low-flow range. Current technologies lack the ability to accurately measure tidal volume but rather provide a semi-quantitative measure of respiratory patterns. A pneumotachograph (which can provide quantitative data) is too burdensome on patient comfort and breathing effort to obtain long term respiration measurements. Self-funded preliminary prototypes were developed prior to this grant submission and tested at the Johns Hopkins Sleep Disorders Center in Baltimore. The prototypes performed comparable to the gold standard (pneumotachograph). This project will finish development of the design, formally benchmark the flow sensor with the pneumotachograph, as well as examine the stability and accuracy of the design. Following this, the design will undergo planned improvements related to patient comfort and compliance. The project will conclude with formal clinical validation studies at overnight sleep clinics across a spectrum of patients to compare and validate the new flow sensor to current technology. Final design modifications will focus on optimization of a "plug-and-play" interface thereby simplifying integration with existing polysomnographic recording units and improving technician ease of use and patient comfort. The data and prototypes generated by this application will ultimately translate into improved care of patients that are susceptible to ventilatory failure and eventually as an ambulatory diagnostic system for patients in the home setting. This flow sensor will have an immediate impact on patient monitoring in sleep laboratories and will further influence diagnostic procedures in pulmonary medicine, anesthesia and other medical disciplines. PUBLIC HEALTH RELEVANCE: The proposed project will develop, formally benchmark and validate a new flow sensor that will allow the medical industry to accurately quantify ventilation. This flow sensor will measure a broad range of respiratory events, including subtle changes of breathing, in both pediatric and adult populations. Initially the flow sensor will be used as a diagnostic tool in the sleep lab environment, while future applications will include the flow sensor as a critical component of patient care in the hospital in-patient and ER as well as an ambulatory diagnostic tool for patients in the home setting.
描述(由申请人提供):本项目的总体目标是开发、正式基准测试和验证一种新的流量传感器,该传感器将准确量化儿科和成人患者人群的不同通气程度。流量传感器是一种简单的非接触式一次性部件,即使在低流量范围内也可提供呼吸活动的定量测量。目前的技术缺乏准确测量潮气量的能力,而是提供呼吸模式的半定量测量。呼吸速度描记器(可以提供定量数据)对患者舒适度和呼吸努力造成的负担太大,无法获得长期的呼吸测量值。自筹资金的初步原型是在提交拨款之前开发的,并在巴尔的摩的约翰霍普金斯睡眠障碍中心进行了测试。原型的性能与金标准(呼吸速度描记器)相当。该项目将完成设计开发,正式将流量传感器与呼吸速度计进行基准测试,并检查设计的稳定性和准确性。在此之后,设计将进行与患者舒适度和依从性相关的计划改进。该项目将在夜间睡眠诊所对一系列患者进行正式的临床验证研究,以比较和验证新的流量传感器与当前技术。最终的设计修改将集中在“即插即用”界面的优化上,从而简化与现有多导睡眠图记录单元的集成,并提高技术人员的易用性和患者的舒适度。该应用程序生成的数据和原型最终将转化为对易受治疗失败影响的患者的改善护理,并最终作为家庭环境中患者的门诊诊断系统。这种流量传感器将对睡眠实验室的患者监测产生直接影响,并将进一步影响肺部医学,麻醉和其他医学学科的诊断程序。公共卫生相关性:拟议的项目将开发,正式基准测试和验证一种新的流量传感器,使医疗行业能够准确地量化通气。该流量传感器将测量广泛的呼吸事件,包括儿童和成人人群的呼吸细微变化。最初,流量传感器将被用作睡眠实验室环境中的诊断工具,而未来的应用将包括流量传感器作为医院住院患者和急诊室患者护理的关键组件,以及家庭环境中患者的门诊诊断工具。
项目成果
期刊论文数量(0)
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