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Histology/Immunohistology

Histology/Immunohistology
组织学/免疫组织学
批准号:
7728855
负责人:
DAVID V GOLD
金额:
$6.58万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-08-01 至 2009-07-31
关键词:
Acetic AcidAcetic AcidsAddressAftercareAliquotAnimalsAntibodiesAntigen-Presenting CellsAntigensApoptosisApplications GrantsAvidinB lymphoid malignancyB-Cell NeoplasmB-LymphocytesBindingBiological AssayBiological MarkersBiological PreservationBiotinBispecific AntibodiesBloodBlood PlateletsBlood specimenBudgetsBuffersCD19 geneCD22 antigenCD22 geneCarbon DioxideCell FractionCell LineCell LineageCellsCentrifugationCharacteristicsClassClinicalClinical PathologyCollectionColon CarcinomaColorComputer AssistedComputer softwareCooperative Human Tissue NetworkCore FacilityCultured CellsCytolysisDataDendritic CellsDensitometryDigestionDisruptionDrug or chemical Tissue DistributionEmulsionsEpithelial CellsEpitopesEpratuzumabEquipmentEquus caballusErythrocytesEthanolExhibitsFicollFixativesFlow CytometryFluorescein-5-isothiocyanateFormalinFox Chase Cancer CenterFreezingFresh WaterFrozen SectionsGenus CapraGlassGlycerolGoatGoldGrowthHLA-DR AntigensHairy Cell LeukemiaHaptensHeatingHematoxylinHematoxylin and Eosin Staining MethodHeterogeneityHigh temperature of physical objectHistologicHistologyHospitalsHousingHydrogen PeroxideImageImmunoassayImmunoglobulin GImmunoperoxidase TechnicsIncubatedIncubatorsIndividualInstitutionLabelLaboratoriesLightLight MicroscopeLinkLiquid substanceLungLymphocyteLymphoidLymphomaMS4A1 geneMalignant - descriptorMalignant NeoplasmsManufacturer NameMarrowMature B-LymphocyteMeasuresMechanicsMethanolMethodsMicroscopyMicrotome - medical deviceModificationMolecularMonoclonal AntibodiesMorphologyMucin-1 Staining MethodMultiple MyelomaMusMyelogenousN-hydroxysuccinimideNormal Horse SerumNormal tissue morphologyNumbersOperative Surgical ProceduresOsmotic ShocksParaffin EmbeddingParaffin TissuePatientsPatternPerformancePeroxidasePeroxidasesPopulationPreparationProceduresProgram Research Project GrantsProgram ReviewsProtocols documentationPurposeRadioimmunoconjugateRadioimmunotherapyRadiolabeledRangeReagentRelative (related person)ReportingResearch PersonnelRetrievalRhodamineRhodaminesRoswell Park Cancer InstituteSCID MiceSerumServicesSlideSodium ChlorideSolid NeoplasmSolutionsSourceSpecimenStaining methodStainsStem cellsStructure of thyroid parafollicular cellStudy SectionSumSurveysSuspension substanceSuspensionsTechniquesTechnologyTemperatureTestingTimeTissue BanksTissue EmbeddingTissue ProcurementsTissue StainsTissuesTracerTranscriptional ActivationTubeTumor MarkersUp-RegulationWaterWeekWorkXenograft procedureanimal tissuecancer typecharge coupled device cameracollagenasecryogenicscryostatdigitalfluorescence microscopefollow-upgranulocyteinstrumentinterestinvariant chainkidney celllight microscopymacrophagemembermicroautoradiographymonoclonal antibody LL2monocyteneoplastic cellparaformperipheral bloodplasma cell differentiationprecursor cellpressureprogramsradiotracerrituximabsarcomasodium phosphatetissue fixingtositumomabtumorvector

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英文摘要
CMMI currently maintains an active Histology Laboratory that has provided various histologic staining imtnunoassay procedures as a service for in-house investigators. This Core Facility will be responsible for tissue procurement, preparation, sectioning, and the performance of immunoenzyme and immunofluorescent assays, microautoradiography, and specialized histochemical procedures. Examination of stained specimens can be carried out by light microscopy, fluorescent microscopy or video densitometer. For the purposes of this grant proposal Dr. Gold, (Core Leader) will review all slides. Additional assistance in the review of stained slides is available from our collaborators in this Program Project, Drs. Ely and Knowles from NY Hospital (NYC, NY). A majority of the specimens for histology services will be provided by members of the Program Project, either from experimental animal and cell culture studies or clinical pathology material to be obtained from Drs. Ely and Knowles of the NY Hospital (NYC, NY). As a yearly average we expect 1250 specimens a year for histology services.
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