Optical Fibre Picorheology

光纤皮流变学

• 批准号: EP/C536266/2
• 负责人: Thomas Waigh
• 金额: --
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FC536266%2F2
• 关键词: Optical; Fibre; Picorheology

Soft materials such as food biopolymer mixtures (eg fruit pastels) and blood clots are both viscoelastic and can thus both store and dissipate energy. Indeed this is vital to their correct functioning in industry and biology. We will build a new device to measure the viscoelasticity of tiny quantities (picolitre) of such materials. It will allow us to construct a picture of how blood clots are formed from ruptured arteries, since the device can be placed at a number of locations in the materials sampling their whole behaviour. The picorheometer functions at such high frequencies (-MHz) that the measurements can probe the internal dynamics of the molecules jiggling around in solution. This will allow us the build models connecting the molecular structure to how they flow when deformed. Blood clots are implicated in a series of medical conditions including hemophilia and strokes. The food industry now uses a large range of sophisticated ideas from theoretical physics to determine the shape and viscosity of foods. The picorheometer will allow foods to be examined dynamically, again allowing new structure/motion models to be built, which can subsequently be related to recipes used in their production.

诸如食品生物聚合物混合物（例如水果粉）和血凝块等软材料都具有粘弹性，因此可以储存和耗散能量。事实上，这对于它们在工业和生物学中的正确运作至关重要。我们将建造一种新设备来测量此类材料的微量（皮升）的粘弹性。它将使我们能够构建一幅关于破裂动脉如何形成血凝块的图片，因为该设备可以放置在材料中的多个位置，以对其整个行为进行采样。皮流变仪在如此高的频率 (-MHz) 下工作，测量结果可以探测溶液中分子抖动的内部动力学。这将使我们能够构建模型，将分子结构与变形时的流动方式联系起来。血栓与一系列疾病有关，包括血友病和中风。食品工业现在使用理论物理学中的大量复杂思想来确定食品的形状和粘度。比流变仪将允许动态检查食物，再次允许建立新的结构/运动模型，随后可以将其与生产中使用的配方相关联。

项目成果

Charge and interfacial behavior of short side-chain heavily glycosylated porcine stomach mucin.

短侧链重糖基化猪胃粘蛋白的电荷和界面行为。

• DOI: 10.1021/bm700721c
• 发表时间: 2007
• 期刊: Biomacromolecules
• 影响因子: 6.2
• 作者: Yakubov GE

Optical coherence tomography picorheology of biopolymer solutions

生物聚合物溶液的光学相干断层扫描图像流变学

• DOI: 10.1063/1.2917578
• 发表时间: 2008
• 期刊: Applied Physics Letters
• 影响因子: 4
• 作者: Sharma R

Molecular structure and rheological properties of short-side-chain heavily glycosylated porcine stomach mucin.

• DOI: 10.1021/bm700607w
• 发表时间: 2007-10
• 期刊: Biomacromolecules
• 影响因子: 6.2
• 作者: G. Yakubov;A. Papagiannopoulos;E. Rat;R. Easton;T. Waigh

Vibrationally selective radiative and non-radiative transitions in gaseous hydrogen molecules.

• DOI: 10.1016/j.saa.2011.02.015
• 发表时间: 2011-08
• 期刊: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
• 作者: Ramesh C. Sharma;T. Waigh;A. Maini;S. Thakur;J. Singh;K. Lin