Affect Regulation Training for Pregnant Smokers

描述（由申请人提供）：最近的数据表明，大约三分之一的育龄妇女吸烟，25-50%的妇女在怀孕期间吸烟。怀孕期间吸烟是一个重大的公共卫生问题，可能对妇女的健康及其发育中的胎儿的健康产生深远影响。孕妇吸烟与高水平的负面影响有关，这在维持吸烟行为和怀孕期间难以戒烟方面起着关键作用。尽管负面情绪在孕妇持续吸烟中扮演着明确的角色，而且这个问题也受到了临床医生和研究人员的越来越多的关注，但我们知道，没有结合应对技能和情绪调节方法的戒烟干预措施来解决负面情绪在戒烟中的作用。已证明对经常吸烟者有效的戒烟治疗策略并未转化为对孕妇，特别是低收入孕妇有效的治疗策略。这个项目的目标是开发和测试一个影响调节戒烟干预低收入怀孕吸烟者。该项目的主要目标将分两个连续阶段实现。在第一阶段，我们将制定两个8期戒烟治疗手册，包括：(a)影响调节训练和认知行为治疗（ART+CBT）和认知行为治疗（CBT）。在第二阶段，我们将进行一项随机临床试验先导研究（总N = 60），比较ART+CBT和CBT的情况：a)干预措施的可行性和可接受性，(b)这些干预措施对治疗后和戒烟后6个月戒烟率的影响，(c)影响调节技能，(d)对怀孕吸烟者的负面影响。这项拟议研究的长期目标是提高怀孕吸烟者的戒烟率，这将为母亲和她们的婴儿提供显著的长期健康益处。第一阶段申请将用于生成可行性和初步疗效数据，为第二阶段疗效试验奠定基础。

DESCRIPTION (provided by applicant): Recent data indicate that approximately one-third of women of childbearing age smoke cigarettes, and 25-50% of women smoke during pregnancy. Cigarette smoking during pregnancy is a significant public health issue that can have profound effects on women's health and the health of their developing fetus. Smoking among pregnant women is associated with high levels of negative affect, which play a key role in the maintenance of smoking behavior and in difficulty quitting smoking during pregnancy. Despite the clear role of negative affect in the maintenance of smoking among pregnant women, and while this issue has received increased attention by clinicians and researchers, we know of no smoking cessation intervention that combines coping skills and emotion regulation approaches to address the role of negative affect in smoking cessation. Smoking cessation treatment strategies that have demonstrated effectiveness in regular smokers have not translated into effective treatment strategies for pregnant women, particularly low-income pregnant women. The goal of this project is to develop and test an affect regulation smoking cessation intervention for low-income pregnant smokers. The major aims of this project will be addressed in two sequential phases. In Phase 1, we will develop two 8-session smoking cessation treatment manuals including: (a) Affect Regulation Training and Cognitive Behavioral Treatment (ART+CBT) and Cognitive-Behavioral Treatment (CBT). In Phase 2, we will conduct a randomized clinical trial pilot study (Total N = 60) to compare the ART+CBT and CBT conditions on: a) the feasibility and acceptability of the interventions, (b) the impact of these interventions on smoking cessation rates at post treatment and at 6-months post-quit date, (c) affect regulation skills, and (d) negative affect among pregnant smokers. The long-term goal of this proposed research is to increase smoking cessation rates among pregnant smokers, which would provide significant long-term health benefits for both mothers and their infants. This Stage 1 application will be used to generate feasibility and preliminary efficacy data, setting the stage for a Stage II efficacy trial.