Supporting and Nurturing Adventurous Chemistry Research in Cardiff

在拨款申请中，我们确定了四个具体的冒险研究项目，并建议在24个月的拨款期内进一步推动冒险研究项目的程序。然而，小组指出，拨款只会用于资助项目3（拨款申请中具体的初步试验研究之一），并要求修改拨款申请的原始摘要，以只反映拟议研究中获资助的部分。项目3：许多重要的材料（包括药物、颜料和其他工业上重要的化合物）是通过溶液形成晶体来制备的。在新材料的设计中，能够在结晶过程中形成的晶体中诱导特定类型的分子形成所需的结构排列是很重要的。要实现这一目标，需要了解结晶过程是如何发生的。不幸的是，我们目前对结晶过程的关键早期阶段所发生的事情了解甚少，因此我们控制这一过程的能力受到严重限制。拟议的项目将评估一个新的想法，通过关注在最终结晶产品形成的过程中最初形成的分子聚集体，来深入了解结晶过程的早期阶段。

In the grant application, four specific adventurous research projects were identified, and procedures for promoting further adventurous research projects during the 24 month period of the grant were also proposed. However, the Panel has indicated that funding will be provided only to support Project 3 (one of the specific initial pilot studies in the grant application), and has requested that the original summary of the grant application should be modified to reflect only the funded component of the proposed research. The summary of this specific funded project is as follows:Project 3: Many important materials (including pharmaceuticals, pigments and other industrially important compounds) are prepared by the formation of crystals from solution. In the design of new materials, it is important to be able to induce a specific type of molecule to form a desired structural arrangement in the crystals that are formed in the crystallization process. To achieve this aim requires an understanding of how crystallization processes occur. Unfortunately, we currently have very little understanding of what happens in the crucial early stages of crystallization processes, and hence our ability to control such processes is severely limited. The proposed project will assess a new idea for gaining insights into the early stages of crystallization processes, by focusing on the molecular aggregates that are initially formed on the way to the formation of the final crystalline product.