THE GUT MICROBIOME IN DEVELOPMENT, HEALTH, AND DISEASE
肠道微生物组在发育、健康和疾病中的作用
基本信息
- 批准号:7614942
- 负责人:
- 金额:$ 2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-09-15 至 2009-08-31
- 项目状态:已结题
- 来源:
- 关键词:AmericanBiologyBiomassCellsChildhoodCommunitiesDataDentistryDermatologyDevelopmentDisciplineDiseaseEnteralGastroenterologyGoalsHealthHepatologyHomeostasisHumanHuman BiologyHuman DevelopmentImmuneImmunologyInflammationInternal MedicineIntestinesKnowledgeLearningMicrobiologyOrganismPediatricsPreparationProbioticsRangeRegulationResearch PersonnelRoleSocietiesTechniquesTrainingcareerconceptfield studyhuman diseaselecturesmicrobialmicrobial hostmicrobiomenutrition
项目摘要
DESCRIPTION (provided by applicant): People contain at least ten-fold more microbial than human cells. Recent data compel serious consideration of co-evolved microbial-host partnerships. We are, in fact, super-organisms and composites of many species. This nascent field of study has tremendous implications for human development, health, homeostasis, and disease, and the human enteric biomass represents the largest fraction of these organisms. For these reasons, we will present a course on the human intestinal microbiome in development, health and disease, in conjunction with the North American Society for Pediatric Gastroenterology Hepatology and Nutrition. The course will be open to a wide community of investigators in pediatrics, internal medicine, immunology, microbiology, dentistry, dermatology, and other fields, and feature lectures from a panel of pioneers in this discipline. Topics to be covered include the role of the intestinal microbiota in intestinal and extraintestinal inflammation, immune regulation, and the biology of probiotics. There will be particular emphasis on trainees, and preparation for careers in this multifacetted field. Biologic concepts related to the study of the intestinal microbiome will be emphasized. It is anticipated that this inaugural course on this topic will prompt a wide range of investigators to obtain training in techniques relevant to this field. Because microbiome studies are changing basic concepts of human biology so rapidly, and because so few trainees in this field are in the pipeline, it is critical that investigators learn about these emerging data, so that they can help convert this information into useful knowledge rapidly and efficiently, which is the goal of the course.
描述(由申请人提供):人体内的微生物比人体细胞至少多十倍。最近的数据迫使人们认真考虑共同进化的微生物-宿主伙伴关系。事实上,我们是超级有机体,是许多物种的混合体。这一新兴的研究领域对人类的发展、健康、体内平衡和疾病有着巨大的影响,而人类肠道生物量代表了这些生物的最大部分。由于这些原因,我们将与北美儿科胃肠病学肝病学和营养学会合作,开设一门关于人类肠道微生物群在发育、健康和疾病中的课程。该课程将面向儿科、内科、免疫学、微生物学、牙科、皮肤病学和其他领域的广泛研究人员开放,并由该学科的先驱小组进行讲座。涉及的主题包括肠道微生物群在肠道和肠外炎症中的作用,免疫调节和益生菌生物学。将特别强调培训生,并为这一多方面领域的职业生涯做准备。与肠道微生物组研究相关的生物学概念将被强调。预计这一主题的首次课程将促使广泛的研究人员获得与该领域相关的技术培训。由于微生物组研究正在如此迅速地改变人类生物学的基本概念,并且由于该领域的培训生太少,因此研究人员了解这些新兴数据至关重要,这样他们就可以帮助将这些信息快速有效地转化为有用的知识,这是本课程的目标。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Lungs, microbes and the developing neonate.
- DOI:10.1159/000381124
- 发表时间:2015
- 期刊:
- 影响因子:2.5
- 作者:Warner BB;Hamvas A
- 通讯作者:Hamvas A
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PHILLIP I TARR其他文献
PHILLIP I TARR的其他文献
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{{ truncateString('PHILLIP I TARR', 18)}}的其他基金
The Neonatal Microbiome and Necrotizing Enterocolitis
新生儿微生物组和坏死性小肠结肠炎
- 批准号:
8134250 - 财政年份:2009
- 资助金额:
$ 2万 - 项目类别:
The Neonatal Microbiome and Necrotizing Enterocolitis
新生儿微生物组和坏死性小肠结肠炎
- 批准号:
8318269 - 财政年份:2009
- 资助金额:
$ 2万 - 项目类别:
The Neonatal Microbiome and Necrotizing Enterocolitis
新生儿微生物组和坏死性小肠结肠炎
- 批准号:
7650793 - 财政年份:2009
- 资助金额:
$ 2万 - 项目类别:
The Neonatal Microbiome and Necrotizing Enterocolitis
新生儿微生物组和坏死性小肠结肠炎
- 批准号:
8111454 - 财政年份:2009
- 资助金额:
$ 2万 - 项目类别:
STRATEGIC TARGETING OF VIRAL GENOMES IN BILIARY ATRESIA
胆道闭锁中病毒基因组的策略性靶向
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7599257 - 财政年份:2008
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$ 2万 - 项目类别:
Pathophysiology of Childhood Hemolytic Uremic Syndrome
儿童溶血尿毒症综合征的病理生理学
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6972016 - 财政年份:2004
- 资助金额:
$ 2万 - 项目类别:
Pathophysiology of Childhood Hemolytic Uremic Syndrome
儿童溶血尿毒症综合征的病理生理学
- 批准号:
6922877 - 财政年份:2003
- 资助金额:
$ 2万 - 项目类别:
Pathophysiology of Childhood Hemolytic Uremic Syndrome
儿童溶血尿毒症综合征的病理生理学
- 批准号:
6613831 - 财政年份:2003
- 资助金额:
$ 2万 - 项目类别:
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