Sixteenth Microbial Genomics Conference - 2008

描述（由申请人提供）：本提案是为将于2008年9月14日至18日在加利福尼亚州箭头湖的加州大学洛杉矶分校会议中心举行的第16届微生物基因组学会议（前身为大肠杆菌和小基因组会议和微生物基因组会议）申请会议经费。基因组学的前景已经发生了变化，现在有大量的基因组可用，微阵列和生物信息学方法正在迅速发展，整个微生物群落都可以在序列水平上进行研究。培养多学科方法来定义和解决问题是及时的。毫无疑问，微生物学不同方面的大量整合将会发生，包括关于进化和生命需求的新观点。为了实现这些目标，特别是整合和协同，来自不同学科的科学家必须相互作用。因此，本次会议将包括活跃的基因组研究人员，如测序专家和信息学专家在数据库设计，序列分析，或模拟工作；遗传学家开发利用基因组信息的新方法，例如用于功能分析；还有细胞生物学家和生物化学家，他们专门研究的领域现在已经成熟，比如代谢、染色体结构或基因调控。本次会议的一个重点将是微生物群落和生物多样性，包括病原体和生物威胁剂。这直接关系到人类的健康。在过去的16年里，这个会议已经成为一个重要的微生物基因组学年度会议，并保证了地位和质量。本次会议讨论微生物的分子遗传学，包括病原体和生物威胁。促进这些微生物的检测和指纹识别的方法，以及了解它们的基因组与它们的功能之间的关系，会议的所有主题都与人类健康直接相关。

DESCRIPTION (provided by applicant): This proposal is for a conference grant for the Sixteenth Microbial Genomics Conference (formerly the E. coli and Small Genomes Conference, and the Microbial Genomes Conference) to be held September 14-18, 2008, at the UCLA conference center at Lake Arrowhead, California. The genomics landscape has changed now that numerous genomes are available and that microarrays and bioinformatics methods are advancing rapidly, and that whole microbial communities are open to investigation at the sequence level. It is timely to foster multi-disciplinary approaches to define and solve problems. Considerable integration of different aspects of microbiology will undoubtedly take place, including new perspectives on evolution and the requirements for life. To achieve these goals, particularly of integration and synergy, scientists from diverse disciplines must interact. Thus, this conference will include active genome researchers, such as sequencing experts and informatics specialists working in database design, sequence analysis, or simulation; geneticists developing new methods to take advantage of genomic information, e.g. for functional analysis; and cell biologists and biochemists who have specialized in areas now ripe for genomics such as metabolism, chromosome structure, or gene regulation. One focus of this conference will be on microbial communities and biodiversity, including pathogens and biothreat agents. This has a direct bearing on human health. This meeting has become established as a major annual microbial genomics conference during the last sixteen years and has assured status and quality. This conference deals with the molecular genetics of microorganisms, including pathogens and biothreats. Methods facilitating the detection and fingerprinting of these microorganisms, as well as understanding how their genomes relate to their functions, all topics at the conference, are directly related to human health.