Plasmid Biology 2008 Symposium

描述(由申请人提供)： 该提案寻求资金支持将于2008年8月30日至9月5日在波兰格但斯克举行的国际质粒生物学大会(质粒生物学2008)。这次会议的目标是将从事所有质粒生物学领域的科学家聚集在一起，讨论该领域的最新进展。质粒是原核生物、真核生物和古生物中发现的一组独特的遗传元件。它们是细菌遗传多样性的主要来源，并负责自然界中各种基因的传播，包括编码抗生素耐药性、毒素和参与细菌毒力的基因。在一些基础生物学研究中，如复制、基因表达和重组等，也可以用质粒作为模型。在与医药/兽医、基因组学、生物技术、农业和环境相关的行业中，质粒也是重要的工具。为了更好地理解它们在自然界中的持续和传播所涉及的分子机制，有必要对质粒生物学进行积极的研究。2008年质粒生物学是每两年举行一次的研讨会的延续，该研讨会每两年举行一次，讨论该领域主要进展的要点。会议将讨论所有方面的质粒生物学，如它们的复制、分配/稳定性、转移、基因组学、进化、生态学、它们作为水平基因库来源的作用，包括抗生素耐药性和毒力基因，细菌毒力的参与，医学和兽医方面，应用方面，以及生物信息学。我们预计将有大约150-200名科学家出席，其中大约一半来自美国，一半来自世界其他地区。没有一个类似的国际会议涵盖了所有的质粒生物学领域。这次会议为国际质粒生物学社区服务，并为交流对该领域的持续发展至关重要的思想提供了一个极好的论坛。过去一次会议的与会者包括该领域的领导人以及年轻科学家、研究生、博士后研究员和少数族裔科学家。会议将包括受邀发言者以及根据提交的摘要选定的发言者。美国国立卫生研究院要求资助10名美国人的旅行费用，其中至少5人将是博士后/博士后学员或少数族裔科学家。美国国立卫生研究院还要求资助另外10名美国人的注册/住宿费用，其中至少有5人将是博士后/博士后学员或少数族裔科学家。因此，我们计划为总共20名美国科学家提供部分支持，为10名个人提供差旅支持，并为另外10名个人提供注册/住宿费用。该提案寻求资金支持将于2008年8月30日至9月5日在波兰格但斯克举行的国际质粒生物学大会(质粒生物学2008)。这次会议的目标是将从事所有质粒生物学领域的科学家聚集在一起，讨论该领域的最新进展。质粒是细菌遗传多样性的主要来源，并负责自然界中各种基因的传播，包括编码抗生素耐药性的基因、毒素和参与细菌毒力的基因。在与医药、兽药、基因组学、生物技术、农业和环境相关的行业中，质粒也是重要的工具。

DESCRIPTION (provided by applicant): This proposal seeks funds to support the International Plasmid Biology Conference (Plasmid Biology 2008) to be held in Gdansk, Poland from August 30th to September 5th 2008. The goals of this meeting are to bring together scientists working in all the areas of plasmid biology to discuss the latest advances in the field. Plasmids represent a unique group of genetic elements found in prokaryotes, eukaryotes and archaeon. They are a major source of genetic diversity in bacteria and are responsible for the spread of a variety of genes in nature, including those encoding antibiotic resistance, toxins and those involved in bacterial virulence. Plasmids also serve as models for basic biological studies such as replication, gene expression, and recombination, to name a few. Plasmids are also important tools in industries related to medicine/veterinary medicine, genomics, biotechnology, agriculture and environment. Vigorous studies on plasmid biology are necessary for a better understanding of the molecular mechanisms involved in their persistence and spread in nature. Plasmid Biology 2008 represents a continuation of the bi-annual symposia held to discuss the highlights of major advances in this field every two years. The meeting will include a discussion of all aspects of plasmid biology such as their replication, partition/stability, transfer, genomics, evolution, ecology, their role as a source of horizontal gene pool, including antibiotic resistance and virulence genes, involvement in bacterial virulence, medical and veterinary aspects, applied aspects, and bioinformatics. We anticipate attendance by approximately 150-200 scientists, approximately one-half from the United States and one-half from the rest of the world. There is no similar international meeting that covers all the areas of plasmid biology. This meeting serves the international plasmid biology community and provides an excellent forum for exchange of ideas that are critical for the continued advances in the field. Participants in the past meeting have included leaders in the field as well as younger scientists, graduate students, postdoctoral fellows and minority scientists. The meeting will include invited speakers as well as speakers selected on the basis of submitted abstracts. NIH funds are requested to support the travel expenses of 10 US individuals, at least 5 of which will be predoctoral/postdoctoral trainees or minority scientists. NIH funds are also requested to support the registration/lodging expenses of 10 additional US individuals, at least 5 of which will be predoctoral/postdoctoral trainees or minority scientists. Thus, we plan to provide partial support for a total of 20 US scientists, providing travel support for 10 individuals and registration/lodging expenses for another 10 individuals. This proposal seeks funds to support the International Plasmid Biology Conference (Plasmid Biology 2008) to be held in Gdansk, Poland from August 30th to September 5th 2008. The goals of this meeting are to bring together scientists working in all the areas of plasmid biology to discuss the latest advances in the field. Plasmids are a major source of genetic diversity in bacteria and are responsible for the spread of a variety of genes in nature, including those encoding antibiotic resistance, toxins and those involved in bacterial virulence. Plasmids are also important tools in industries related to medicine, veterinary medicine, genomics, biotechnology, agriculture and environment.