Environmental Endocrine Disrupters 2008 Gordon Research Conference

环境内分泌干扰物 2008 年戈登研究会议

• 批准号: 7481660
• 负责人: Shanna H Swan
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7481660
• 关键词: Adult; Aging; Amendment; Animal Model; Anniversary; Area; Basic Science; Brain; Chemicals; Development; Dimensions; End Point; Endocrine Disruptors; Endocrine disruption; Environmental Health; Europe; European Union; Event; Food; Goals; Government; Growth; Health; Immune; In Vitro; Institutes; International; Investigation; Japan; Laws; Metabolic; Methods; Names; National Institute of Child Health and Human Development; New Hampshire; Numbers; Philosophy; Play; Population; Positioning Attribute; Proceedings and Conferences; Proceedings, Conference; Publications; Published Comment; Range; Reporting; Research; Resort; Risk; Role; Science; Scientist; Shapes; System; Testing; Thinking; Thyroid Gland; United States; Water; body system; bone; cancer type; design; drinking water; exposed human population; female reproductive system; food quality; interest; male; multidisciplinary; novel; planetary Atmosphere; symposium; unpublished works

DESCRIPTION (provided by applicant) The sixth Gordon Research Conference (GRC) on Environmental Endocrine Disruptors (EED) will be held June 8-13, 2008, in Waterville Valley Resort, New Hampshire. It was designed to achieve two goals. First, this conference will mark the 10th anniversary of the first GRC on EED, an event that has markedly influenced the growth of this field of research. One example: between 1998 and 2006 the annual number of Medline citations for the key words "endocrine disruption/disruptors" has grown by twenty-fold. To maintain this pace of growth, the 2008 conference seeks to highlight the important advances over that period and to help shape the next decade of research. Second, the conference aims to highlight the most recent science through discussions of new candidate EEDs, newly discovered and proposed mechanisms of action, new endpoints under investigation as targets of EEDs, and new methods for evaluating health and ecological risks attributable to EED exposure. The list of speakers includes leading scientists from the US, Japan and Europe, as well as young scientists who have recently reported exciting findings. Endocrine disruptors are now thought to influence the development of not only male and female reproductive systems, but also to be involved in the development and adult functions of numerous organ systems (including metabolic, immune and thyroid, bone, and brain), as well as playing a role in the onset and progression of several types of cancers. Governments of the United States, Japan and the European Union have enacted laws regulating endocrine disrupters (most recently REACH) and in the U.S., amendments were passed to the Safe Drinking Water Act and the Food Quality Protection Act mandating the testing of chemicals found in water and food for endocrine-disrupting activity. Public interest in endocrine disruptors has grown at the same pace as the science. The GRC represents a unique venue for promoting research and the exchange of information and viewpoints in this critical area of environmental health. The proposed conference adheres to the guiding principle of the GRC that the presentations are to be of new, unpublished work and that the discussions are to be open and unhampered. There is a tradition of freely sharing ideas in an "off the record" atmosphere, without the constraining publication of conference proceedings. This underlying philosophy is critical because the proposed topics are positioned at the cutting edge of current science. The proposed conference embodies a subject area with interdisciplinary and multidisciplinary dimensions, and will convene a diverse group of international scientists whose studies and interests range from effects in and exposures of human populations, to ecological effects and exposures in wildlife. These interests extend to basic research in animal models and novel in vitro systems. In addition to the NIEHS, this conference is of potential interest to the National Institute on Aging (NIA) and the National Institute of Child Health and Human Development (NICHD), both of which have agreed to be named as secondary on this application.

描述（由申请人提供） 第六届戈登环境内分泌干扰物研究会议（GRC）将于2008年6月8日至13日在新罕布什尔州的沃特维尔山谷度假村举行。 它旨在实现两个目标。首先，本次会议将纪念第一届GRC EED十周年，这一事件显着影响了这一研究领域的发展。举个例子：在1998年至2006年期间，Medline对关键词“内分泌干扰/干扰物”的年度引用数量增长了20倍。为了保持这种增长速度，2008年的会议旨在强调这一时期的重要进展，并帮助塑造下一个十年的研究。第二，会议旨在通过讨论新的候选EED，新发现和提出的作用机制，正在调查的EED目标的新终点，以及评估EED暴露引起的健康和生态风险的新方法，来突出最新的科学。演讲者名单包括来自美国，日本和欧洲的领先科学家，以及最近报告了令人兴奋的发现的年轻科学家。内分泌干扰物现在被认为不仅影响男性和女性生殖系统的发育，而且还参与许多器官系统（包括代谢，免疫和甲状腺，骨骼和大脑）的发育和成年功能，以及在几种类型癌症的发病和进展中发挥作用。美国、日本和欧盟政府已经颁布了管理内分泌干扰物的法律（最近的是REACH），在美国，通过了《安全饮用水法》和《食品质量保护法》的修正案，规定对水和食品中发现的化学品进行内分泌干扰活性测试。公众对内分泌干扰物的兴趣与科学的发展速度相同。该研究中心是一个独特的场所，以促进研究和交流信息和观点，在这一关键领域的环境卫生。拟议的会议坚持GRC的指导原则，即演讲是新的，未发表的工作，讨论是开放和不受阻碍的。有一种在“非正式”气氛中自由交流想法的传统，而不限制会议记录的出版。这一基本哲学是至关重要的，因为所提出的主题位于当前科学的前沿。拟议的会议体现了一个具有跨学科和多学科层面的主题领域，并将召集一批不同的国际科学家，他们的研究和兴趣范围从对人类的影响和暴露到对野生动物的生态影响和暴露。这些兴趣延伸到动物模型和新型体外系统的基础研究。除了NIEHS，本次会议是潜在的兴趣，以国家老龄化研究所（NIA）和国家儿童健康和人类发展研究所（NICHD），这两个都已同意被命名为次要的这个应用程序。