BioPAX - Biological Pathway Community Workshop

路径信息对于理解生物系统至关重要。不幸的是，超过170在线 途径数据资源在生物过程的覆盖范围和代表性方面差异很大， 用于解决生物问题极其困难。BioPAX组是通过以下途径形成的 2002年11月，数据库社区开发了一个标准的生物途径数据交换格式， 通过一系列的小型研讨会来解决这个问题。这导致了社区的发展 公认的开源BioPAX 1级交换格式，支持代谢途径数据， BioPAX 2级，增加了对分子相互作用数据的支持。我们寻求支持的一个研讨会系列 2006年、2007年和2008年。本系列会议的目标是扩展BioPAX数据模型 通过增加对信号通路、基因调控网络和遗传相互作用的支持， 上位性;增加对.BioPAX的数据库和工具支持;并鼓励公开 可访问的途径数据及其在生物学问题中的应用。我们建议举办BioPAX研讨会 一年两次，每次持续两天。这些将侧重于通过BioPAX数据模型实现我们的目标 社区发展讨论。每年一次讲习班将包括一次专题讨论会， 演讲者讨论他们的途径相关的计算研究。会议将包括哈克， 其中协作开发诸如数据库转换器之类的计算机软件。会议将 主办的参与者和地点将通过SRI，门洛帕克，加利福尼亚州（彼得卡普），冷泉循环 Harbor Labs，纽约，NY（林肯Stein）和Memorial-Sloan Kettering癌症中心，纽约，NY （Chris Sander）或其他方便的美国地点。所有会议将开放给社区参与， 所有会议记录和由此产生的工作都可以通过www.biopax.org网站在开放源码条款下免费获得。

Pathway information is vital for understanding biological systems. Unfortunately,the over 170 online pathway data resourcesvary widely in coverage and representation of biological processes, making their use for biological problem solving extremely difficult. The BioPAX groupwas formed by the pathway database community in November 2002 to develop a standard biological pathway data exchangeformat to solve this issue through a series of small workshops. This has resulted in the development of the community accepted, open-source BioPAX level 1 exchange format, which supports metabolic pathway data and BioPAX level 2, which adds support for molecular interaction data. We seek support for a workshop series for the years 2006, 2007 and 2008. The goals of this meeting series are to expandthe BioPAX data model by adding support for signaling pathways, gene regulation networks and genetic interactions, such as epistasis; to increase database and tool support for.BioPAX; and to encourage the growth of publicly accessible pathway data and its application to biological problems. We propose to hold BioPAX workshops twice a year, each lasting two days. These will focus on achieving our goals through BioPAX data model and community development discussions. One workshop per year will include a symposium of invited speakers discussing their pathway related computational research. Meetings will include ahackathon, where computer software, such as database converters, is collaboratively developed. Meetings will be hosted by participants and locationswill cycle through SRI, Menlo Park, CA (Peter Karp), Cold Spring Harbor Labs, New York, NY (Lincoln Stein) and Memorial-Sloan Kettering Cancer Center, New York, NY (Chris Sander) or other convenient US locations. All meetings will be open to community participation and all minutes and resulting work is freely available under open sourceterms via the www.biopax.org website.