Visit to Kavli ITP research program Cardiac Dynamics

参观 Kavli ITP 研究项目 Cardiac Dynamics

• 批准号: EP/E016391/1
• 负责人: Vadim Biktashev
• 金额: $ 0.82万
• 依托单位: University of Liverpool
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FE016391%2F1
• 关键词: Visit; Kavli; ITP; research; program

Cardiac disease is a major cause of premature death. More than half of cardiac disease deaths are sudden and result from a spatiotemporally chaotic wave activity that prevents the main chambers of the heart from pumping blood normally (ventricular fibrillation). Developing a fundamental understanding of the mechanisms that trigger and maintain life-threatening cardiac arrhythmias is crucially important for designing antiarrhythmic therapies that successfully reduce mortality.Kavli Institute of Theoretical Physics of the University of California Santa Barbara holds a miniprogram on Cardiac Dynamics dedicated to this agenda, in July-August, 2006. The purpose of the miniprogram is to bring together theoreticians and experimentalists working on cardiac arrhythmias and fibrillation. The applicant is one of the few leading theoreticians invited to participate for the whole duration of the program. KITP provides a partial financial support of this visit, and the current application is for rest of the support required.

心脏病是导致过早死亡的主要原因。超过一半的心脏病死亡是突然的，是由于时空混乱的波活动导致心脏主要腔室无法正常泵血（心室颤动）。对触发和维持危及生命的心律失常的机制有一个基本的了解，对于设计成功降低死亡率的抗心律失常疗法至关重要。加州大学圣巴巴拉分校的Kavli理论物理研究所在2006年7 - 8月举办了一个心脏动力学的小项目，致力于这个议程。这个小程序的目的是把从事心律失常和纤颤研究的理论家和实验家聚集在一起。申请人是少数被邀请参加整个项目期间的主要理论家之一。KITP为这次访问提供部分财政支持，目前的申请是提供所需的其余支持。

项目成果

Dynamics of cardiac re-entry in micro-CT and serial histological sections based models of mammalian hearts

基于微型 CT 和连续组织切片的哺乳动物心脏模型中心脏折返的动力学

• DOI: 10.48550/arxiv.1809.01186
• 发表时间: 2018
• 作者: Ramlugun G

Response function framework for the dynamics of meandering or large-core spiral waves and modulated traveling waves.

• DOI: 10.1103/physreve.99.022217
• 发表时间: 2019-01
• 期刊: Physical review. E
• 作者: H. Dierckx;A. Panfilov;H. Verschelde;V. Biktashev;I. Biktasheva