Laser Induced Beams of Radiation and their Applications (LIBRA

激光诱导辐射束及其应用（LIBRA

• 批准号: EP/E035728/1
• 负责人: Marco Borghesi
• 金额: $ 599.79万
• 依托单位: Queen's University Belfast
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2007
• 资助国家: 英国
• 起止时间: 2007 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FE035728%2F1
• 关键词: Laser; Induced; Beams; Radiation; their

Recent experiments have demonstrated that by shining powerful laser beams on small physical targets (e.g. metals, plastics or liquids), intense energetic beams of ionizing radiation (e.g. beams of ions, protons, neutrons, electrons, gamma and x-rays) are produced. The type of radiation emitted depends on the dimensions and composition of the targets; these factors also determine the unique spatial and temporal properties of the radiation sources, which have an extremely small size (of micrometer order - a millionth of a meter) and emit ultra-short radiation bursts (of picosecond duration, i.e. a millionth of a millionth of a second). Development of basic source technology will provide compact and flexible sources with optimal properties for use in industrial and medical context. We identify protons, ions and gamma rays as the products with the highest potential benefit to society, and will concentrate our efforts on developing sources of these radiation types. Applications of this technology are envisaged in the following areas:Medicine - improved cancer treatment using laser-energised protons and ions, at a significantly lower cost than currently achieved and with reduced radiation shielding requirements;radiobiology studies using multiple simultaneous radiations to simulate cosmic ray effects during air and space travelIndustry - in-situ flash radiography, satellite radiation hardness testing, engineering diagnostics, semiconductor production and manufacturing controlScience - opportunities for versatile production of intense, synchronised beams from a robust and compact source, allowing novel experiments requiring simultaneous delivery of different types of radiation (pump-probe experiments).Security - rapid imaging detection of hidden materials/explosives using gamma-ray tomography and activation techniques for rapid chemical analysis.The proposed project aims to develop the relevant technology for high-flux, high-repetition source delivery and characterisation, while achieving the standards of output beam quality and reliability essential for the above applications. These will be achieved via a combination of innovative developments in target production and delivery, detector technology, beam property optimization and control.

最近的实验表明，通过将强大的激光束照射在小型物理目标（例如金属、塑料或液体）上，会产生强能量的电离辐射束（例如离子、质子、中子、电子、伽马和X射线束）。射线）。发射的辐射类型取决于目标的尺寸和组成;这些因素还决定了辐射源独特的空间和时间特性，这些辐射源具有极小的尺寸（微米级-百万分之一米），并发射超短辐射脉冲（皮秒持续时间，即百万分之一秒）。基础源技术的发展将提供具有最佳性能的紧凑和灵活的源，用于工业和医疗领域。我们认为质子、离子和伽马射线是对社会具有最大潜在效益的产品，并将集中精力开发这些辐射类型的来源。医疗-利用激光激发的质子和离子改进癌症治疗，成本比目前低得多，辐射屏蔽要求降低;放射生物学研究使用多个同时辐射来模拟空气和太空旅行期间的宇宙射线效应工业-原位闪光射线照相术，卫星辐射硬度测试，工程诊断，半导体生产和制造控制科学-从坚固紧凑的光源中生产多用途的高强度同步光束的机会，允许需要同时递送不同类型的辐射的新颖实验（泵浦探测实验）。安全-利用伽马射线断层摄影术和活化技术快速成像探测隐藏的材料/爆炸物，以进行快速化学分析。拟议项目旨在开发高通量、高重复率源的交付和表征，同时达到标准的输出光束质量和可靠性的基本上述应用。这些目标将通过在目标生产和交付、探测器技术、束流特性优化和控制方面的创新发展来实现。

项目成果

Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma.

• DOI: 10.1186/1748-717x-8-65
• 发表时间: 2013-03-19
• 期刊: Radiation oncology (London, England)
• 作者: Barazzuol L;Jena R;Burnet NG;Meira LB;Jeynes JC;Kirkby KJ;Kirkby NF
• 通讯作者: Kirkby NF

Coherent transition radiation in relativistic laser-solid interactions

• DOI: 10.1088/0741-3335/54/3/035011
• 发表时间: 2012-03-01
• 期刊: PLASMA PHYSICS AND CONTROLLED FUSION
• 影响因子: 2.2
• 作者: Bellei, C.;Davies, J. R.;Najmudin, Z.
• 通讯作者: Najmudin, Z.

Optical trapping of laser targets under vacuum for ion-beam production in the LIBRA programme

LIBRA 计划中用于离子束生产的真空下激光目标的光学捕获

• 作者: Andrew Ward (Author)

Energetic beams of negative and neutral hydrogen from intense laser plasma interaction

• DOI: 10.1063/1.4850456
• 发表时间: 2013-12-16
• 期刊: APPLIED PHYSICS LETTERS
• 影响因子: 4
• 作者: Abicht, F.;Prasad, R.;Ter-Avetisyan, S.
• 通讯作者: Ter-Avetisyan, S.

Stabilized Radiation Pressure Acceleration and Neutron Generation in Ultrathin Deuterated Foils.

超薄氘化箔中稳定的辐射压力加速和中子产生。

• DOI: 10.1103/physrevlett.129.114801
• 发表时间: 2022
• 期刊: Physical review letters
• 影响因子: 8.6
• 作者: Alejo A