Physical Organic Chemistry: Opportunities in Synthesis, Materials and Pharmaceuticals

物理有机化学：合成、材料和制药领域的机会

• 批准号: EP/E036244/1
• 负责人: John Murphy
• 金额: $ 338.64万
• 依托单位: University of Strathclyde
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2007
• 资助国家: 英国
• 起止时间: 2007 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FE036244%2F1
• 关键词: Physical; Organic; Chemistry; Opportunities; Synthesis

This application aims to catalyse and sustain a new dimension in UK research capability in physical organic chemistry. Our strategic alliance in physical organic chemistry will provide a unique continuum of expertise to tackle research opportunities in areas as diverse as materials chemistry, synthesis methodologies and pharmaceutical discovery and development. It will have the capability to address issues from solid-state to solution and gas-phase, from small molecules to biopolymers, and from nanoscale to pilot plant. We focus on topics of international significance to industry worldwide as well as to academic chemistry, that will help to (i) drive the creation of 21st-century electronic materials, devices and technologies (ii) understand and exploit methodologies for assisting chemical reactions with the potential to revolutionise energy use in chemicals and pharmaceuticals industries (iii) provide new and more effective medicines through understanding molecular recognition in pharmaceutical systems including drug-receptor, drug-drug and drug-carrier complexes. Its importance is underlined by the initial substantial support from diverse sectors of the chemicals and pharmaceuticals industry that we have so far put in place. It will initially lead to 26 new appointments, and we look forward to even more dynamic growth as the program unfolds.

该应用程序旨在催化和维持英国物理有机化学研究能力的新维度。我们在物理有机化学方面的战略联盟将提供独特的专业知识，以解决像材料化学，合成方法和药物发现和开发等多样性领域的研究机会。它将有能力解决从固态到溶液和气相的问题，从小分子到生物聚合物，以及从纳米级到试验工厂的问题。我们专注于对全球行业以及学术化学具有国际意义的主题，这将有助于（i）创建21世纪的电子材料，设备和技术（II）理解和利用方法，以帮助化学反应，从而有可能通过在化学和药物工业（II II）中革新能源使用的能源（III）的潜力，以革命性地使用分类药物（III II），该系统具有分类物质，以跨性别的药物来跨性别药物（III II，III）。药物和药物载体复合物。到目前为止，我们已经建立了化学品和制药行业的各个部门的最初实质性支持强调了它的重要性。它最初将导致26个新的任命，随着计划的展开，我们期待着更具动态的增长。

项目成果

Synthesis and characterisation of new diindenodithienothiophene (DITT) based materials

• DOI: 10.1039/b919574b
• 发表时间: 2010-01-01
• 期刊: JOURNAL OF MATERIALS CHEMISTRY
• 作者: Afonina, Irina;Skabara, Peter J.;Hursthouse, Michael B.
• 通讯作者: Hursthouse, Michael B.

Direct C-H metalation with chromium(II) and iron(II): transition-metal host/benzenediide guest magnetic inverse-crown complexes.

• DOI: 10.1002/anie.200805566
• 发表时间: 2009
• 期刊: Angewandte Chemie (International ed. in English)
• 作者: Alborés P;Carrella LM;Clegg W;García-Alvarez P;Kennedy AR;Klett J;Mulvey RE;Rentschler E;Russo L
• 通讯作者: Russo L

Convenient synthesis of EDOT-based dyes by CH-activation and their application as dyes in dye-sensitized solar cells

• DOI: 10.1039/c6ta04483b
• 发表时间: 2016-10
• 期刊: Journal of Materials Chemistry
• 作者: S. Abdalhadi;A. Connell;Xiaolu Zhang;A. Wiles;M. Davies;P. Holliman;G. Cooke