Physical Organic Chemistry: Opportunities in Synthesis, Materials and Pharmaceuticals

物理有机化学：合成、材料和制药领域的机会

• 批准号: EP/E036244/1
• 负责人: John Murphy
• 金额: $ 338.64万
• 依托单位: University of Strathclyde
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2007
• 资助国家: 英国
• 起止时间: 2007 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FE036244%2F1
• 关键词: Physical; Organic; Chemistry; Opportunities; Synthesis

This application aims to catalyse and sustain a new dimension in UK research capability in physical organic chemistry. Our strategic alliance in physical organic chemistry will provide a unique continuum of expertise to tackle research opportunities in areas as diverse as materials chemistry, synthesis methodologies and pharmaceutical discovery and development. It will have the capability to address issues from solid-state to solution and gas-phase, from small molecules to biopolymers, and from nanoscale to pilot plant. We focus on topics of international significance to industry worldwide as well as to academic chemistry, that will help to (i) drive the creation of 21st-century electronic materials, devices and technologies (ii) understand and exploit methodologies for assisting chemical reactions with the potential to revolutionise energy use in chemicals and pharmaceuticals industries (iii) provide new and more effective medicines through understanding molecular recognition in pharmaceutical systems including drug-receptor, drug-drug and drug-carrier complexes. Its importance is underlined by the initial substantial support from diverse sectors of the chemicals and pharmaceuticals industry that we have so far put in place. It will initially lead to 26 new appointments, and we look forward to even more dynamic growth as the program unfolds.

该应用程序旨在促进和维持英国物理有机化学研究能力的新维度。我们在物理有机化学领域的战略联盟将提供独特的连续专业知识，以应对材料化学、合成方法以及药物发现和开发等多个领域的研究机会。它将有能力解决从固态到溶液和气相、从小分子到生物聚合物、从纳米级到中试工厂的问题。我们专注于对全球工业和学术化学具有国际意义的主题，这将有助于（i）推动21世纪电子材料、设备和技术的创造（ii）了解和开发辅助化学反应的方法，有可能彻底改变化学品和制药行业的能源使用（iii）通过了解药物系统（包括药物受体）中的分子识别来提供新的和更有效的药物， 药物-药物和药物-载体复合物。我们迄今为止所提供的化学品和制药行业各个部门的初步大力支持凸显了其重要性。最初将产生 26 个新任命，我们期待随着该计划的展开，出现更加充满活力的增长。

项目成果

Synthesis and characterisation of new diindenodithienothiophene (DITT) based materials

• DOI: 10.1039/b919574b
• 发表时间: 2010-01-01
• 期刊: JOURNAL OF MATERIALS CHEMISTRY
• 作者: Afonina, Irina;Skabara, Peter J.;Hursthouse, Michael B.
• 通讯作者: Hursthouse, Michael B.

Direct C-H metalation with chromium(II) and iron(II): transition-metal host/benzenediide guest magnetic inverse-crown complexes.

• DOI: 10.1002/anie.200805566
• 发表时间: 2009
• 期刊: Angewandte Chemie (International ed. in English)
• 作者: Alborés P;Carrella LM;Clegg W;García-Alvarez P;Kennedy AR;Klett J;Mulvey RE;Rentschler E;Russo L
• 通讯作者: Russo L

Convenient synthesis of EDOT-based dyes by CH-activation and their application as dyes in dye-sensitized solar cells

• DOI: 10.1039/c6ta04483b
• 发表时间: 2016-10
• 期刊: Journal of Materials Chemistry
• 作者: S. Abdalhadi;A. Connell;Xiaolu Zhang;A. Wiles;M. Davies;P. Holliman;G. Cooke