Lifelong Diabetes Self-Management Intervention

描述（由申请人提供）： 翠西亚·S Tang博士是一名初级研究员，在少数民族癌症预防和控制方面具有研究经验。她正在申请K23奖，以支持她在少数民族和其他高危人群中从事糖尿病翻译研究的决定。国际知名的糖尿病研究人员罗伯特安德森博士将担任她的导师。在1-2年，唐博士将获得糖尿病的病因和治疗，流行病学，研究方法和生物统计学的基础。在第1-5年，她将进行所述的拟议研究，并利用她的数据准备R 01/R18提交资料。 糖尿病是一种慢性疾病，在美国会造成严重的健康、残疾和经济损失。非裔美国人受糖尿病的影响不成比例，因为他们患糖尿病的可能性是白色人的两倍，并且患有更大的糖尿病相关并发症。1糖尿病自我管理干预措施已被证明对知识，血糖监测，饮食行为和血糖控制只有短期的积极影响。2 -5这项研究将检查基于社区，自我管理干预（终身管理）的城市成年人（主要是非洲裔美国人）与2型糖尿病，维持，在长期糖尿病相关的健康收益实现了以前的短期病人教育计划。具体目标： 具体目标1：研究6个月的终身管理（LM）干预与6个月的注意力控制期相比，在改善城市非裔美国成年2型糖尿病患者的血糖控制和生活质量方面的相对疗效。 具体目标二：研究LM干预前6个月取得的收益是否在长期（18个月）内持续或增强。 具体目标3：检查LM干预结束后一年内血糖控制和生活质量是否下降。 具体目标4：检查LM干预的成本和潜在的医疗保健节省。

DESCRIPTION (provided by applicant): Tricia S. Tang, Ph.D. is a junior faculty research investigator with research experience in cancer prevention and control among ethnic minorities. She is applying for a K23 award to support her decision to pursue a career in diabetes translation research among ethnic minority and other high-risk populations. Dr. Robert Anderson, an internationally known diabetes researcher, will serve as her mentor. In the Years 1-2, Dr. Tang will acquire a foundation in causes and treatment of diabetes, epidemiology, research methods, and biostatistics. In Years 1-5, she will conduct her proposed research described and utilize her data to prepare a R01/R18 submission. Diabetes is a chronic disease that incurs significant health, disability, and financial costs in the United States. African Americans are disproportionately affected by diabetes as they are two times more likely to have diabetes that their White counterparts and the suffer greater diabetes-related complications.1 Diabetes self-management interventions have shown to have only short-term positive effects on knowledge, blood glucose monitoring, dietary behavior, and glycemic control.2-5 This study will examine the efficacy of a community-based, self-management intervention (Lifelong Management) for urban adults (primarily African Americans) with type 2 diabetes that sustains, over the long-term diabetes-related health gains achieved by previous short-term patient education programs. Specific aims: Specific Aim 1: To examine the relative efficacy of 6-months of the Lifelong Management (LM) intervention compared to 6-months of an attention-control period in improving glycemic control and quality of life for urban African-American adults with type 2 diabetes. Specific Aim 2: To investigate whether gains achieved from the first 6-months of the LM intervention are sustained or enhanced over the long-term (18-months). Specific Aim 3: To examine whether glycemic control and quality of life decline during the year following the end of the LM intervention. Specific Aim 4: To examine the costs and potential health care savings of the LM intervention.