University of Iowa Clinical and Translational Science Program (TL1)

A.宗旨和职能 临床和转化研究所将培养高度积极的临床研究学者， 以患者为中心的研究中的创新职业。培训计划将提供全面的课程 在一系列临床研究领域，以及丰富的机会，由导师密切监督，从 牙医学院、护理学院、药剂学院、公共卫生学院、工程学院、文理学院，以及 卡佛医学院。学者将从各种临床学科中选出，包括 传统上在临床研究中代表性不足，如放射学，儿科学，临床心理学，外科学 麻醉学和药剂学。培训计划还将覆盖 社区和护士研究协调员。该计划将包括一个K12组件，T32组件， 为期一年的证书课程，以及各种短期研究经验。六个具体功能 研究所的培训方案是： 1)确定和招聘来自不同背景和学科的杰出学者，包括性别和 种族，谁希望获得的原则和学术临床和技术的理解， 转化研究 2)在临床研究的理论和方法，研究伦理， 基本的职业发展技能，如赠款写作 3)提供多学科和综合的指导研究经验，促进发展 学者的研究技能和更广泛的职业发展 4)支持学者在他们的'培训和过渡，通过研究所从学员到独立 调查员，包括通过及时晋升表彰成绩 5)增加训练有素的临床和转化研究学者的人才库，这些学者将反过来创造自我维持的， 创新的多学科研究和培训计划 目前的应用程序将在临床和转化研究教育中创造新的协同效应， 爱荷华州的大学汇集了一些成功的培训计划，包括研究生 转化生物医学项目，K30爱荷华州学者临床研究项目， Doris杜克临床研究奖学金和NCRR资助的K12项目。这些元素的结合 该计划将导致在临床和转化科学新的硕士和博士学位。除了 将临床研究培训纳入一个单一的保护伞下，该研究所将创造一个充满活力的知识分子 有成就的高级导师，初级教师和研究学者谁将进行跨学科， 前沿的转化研究 学位课程的学者将获得核心教学课程，包括五个调查领域的课程 (see下图2.1-1）。核心课程将包括流行病学、生物统计学、临床流行病学， 生物信息学、伦理学和研究生存技能。所有学者将完成核心课程和选修课 在特定的轨道上。然而，培训的特点将是指导研究实习指导， 是30位享誉全国的资深科学家之一导师将是核心或附属学院的教师， 在出版，资助，跨学科研究和培养年轻科学家方面有着良好的记录。

A. Purpose and Functions The Institute for Clinical and Translational Research will train highly motivated clinical research scholars for innovative careers in patient-focused research. The training programs will provide a comprehensive curriculum across a spectrum of clinical research fields, and abundant opportunities for close supervision by mentors from the Colleges of Dentistry, Nursing, Pharmacy, Public Health, Engineering, Liberal Arts and Sciences, and the Carver College of Medicine. Scholars will be selected from a variety of clinical disciplines, including those traditionally underrepresented in clinical research such as radiology, pediatrics, clinical psychology, surgical sub-specialties, anesthesiology, and pharmacy. Training programs will also reach health care providers in the community and nurse research coordinators. The program will include a K12 component, T32 component, year-long certificate program, and a variety of short-term research experiences. The six specific functions of the Institute's training programs are to: 1) Identify and recruit outstanding scholars from diverse backgrounds and disciplines, inclusive of gender and ethnicity, who wish to obtain an understanding of the principles and techniques of scholarly clinical and translational research 2) Implement a didactic curriculum in the theories and methods of clinical research, research ethics, and essential career development skills, such as grant writing 3) Provide multidisciplinary and integrated mentored research experiences that facilitate the development of scholars' research skills and their broader career development 4) Support scholars in their'training and transition through the Institute from mentee to independent investigator, including recognition of achievement by timely promotion 5) Increase the pool of well-trained clinical and translational research scholars who will in turn create selfsustaining, innovative, multidisciplinary research and training programs The current application will create new synergies in clinical and translational research education at The University of Iowa by bringing together a number of successful training programs, including the Graduate Program in Translational Biomedicine, the K30 Iowa Scholars in Clinical Investigation Program, the Doris Duke Clinical Research Fellowship, and a NCRR-funded K12 Program. The coalescence of these programs will result in new master's and PhD degrees in Clinical and Translational Science. In addition to bringing clinical research training under a single umbrella, the Institute will create a vibrant intellectual community of accomplished senior mentors, junior faculty, and research scholars who will undertake crossdisciplinary, cutting-edge translational research. Scholars in the degree programs will receive a core didactic curriculum with tracks in five areas of investigation (see Figure 2.1-1 below). The core curriculum will include epidemiology, biostatistics, clinical epidemiology, bioinformatics, ethics, and research survival skills. All scholars will complete the core curriculum and elective courses in a particular track. However, the hallmark of training will be a mentored research practicum directed by one of 30 senior scientists with national reputations. Mentors will be core or affiliated Institute faculty with strong track records in publication, funding, cross-disciplinary research, and nurturing young scientists.