Interdisciplinary Anesthesiology Research Training Program

麻醉学是一门跨学科的学科，它的从业者需要有广泛的 跨越药理学、生理学和工程学的知识，能够将这些知识应用于 无论是受控情况还是紧急情况。除了为学员提供非凡的临床知识外， 加州大学旧金山分校麻醉学系以及更大的学术社区 迭戈大学(UCSD)，为发展高质量的研究培训提供了世界级的环境。 加州大学圣迭戈分校的两个特别的基础科学研究优势包括药理学和 工程学。麻醉师，包括基础科学家和临床医生，都有长期的互动。 与这两个学科的教职员工的合作反映了 麻醉学，使用药剂来最好地管理病人并发明和创造解决方案 这需要工程技术来加强对病人的护理。我们的互动和合作跨越了 资深教员、初级内科科学家、研究员和住院医师。因此，这笔T32赠款的主要目标是 申请是将加州大学圣迭戈分校一直在进行的研究培训正规化并提升到下一个水平 特别是在麻醉学系与药理学和工程学合作。这 培训补助金将为研究生实习生(医学博士或医学博士)提供为期两年的研究经验 包括广泛关注药物作用的基本分子机制和/或探索各种 工程学科。重点是定义对药物作用机制的新见解， 可以导致治疗干预措施的开发和应用工程原理来制造设备， 使用数学和理论方法建立生理学和病理生理学模型，研究 便于生物材料的非侵入性监测和生物特征数据的生成等。 从角度来看，为了实现这一总体目标，培训经历有两个具体目的：i)让学员接触到 在新闻部和整个校园特别存在的科学和调查文化，以及二) 具备研究生涯相关要素的能力，例如实验设计、数据分析、 演讲，手稿准备和出版，以及如何最好地获得研究资金和实验室 管理和面试技巧。重要的是，我们强烈强调联合领导和道德问题。 研究环境。在实现我们对临床医生科学家发展的坚定承诺中，我们的 最重要的任务是培养下一代临床医生科学家，他们具有 知识和基本工具，再加上影响翻译研究的热情和承诺。

Anesthesiology is an interdisciplinary discipline that requires its practitioners to have a broad fund of knowledge that traverses pharmacology, physiology, and engineering with the ability to apply this knowledge in both controlled and emergency situations. In addition to providing trainees with exceptional clinical knowledge, the Anesthesiology Department as well as the larger academic community at the University of California, San Diego (UCSD), provides a world-class environment for the development of high quality training in research. Two particular basic science research strengths at UCSD include the Departments of Pharmacology and Engineering. Anesthesiologists including both basic scientists and clinicians have long standing interactions and collaborations with faculty in these two disciplines as the interests mirror the major clinical concerns of anesthesiology, the use of pharmacologic agents to best manage patients and to invent and create solutions that require engineering to enhance patient care. Our interactions and collaborations have spanned established faculty, junior physician scientist, fellows and residents. Thus, the primary goal of this T32 grant application is to formalize and take to the next level research training that has been occurring at UCSD and specifically in the Department of Anesthesiology with collaboration in Pharmacology and Engineering. This training grant will provide post-graduate trainees (MDs or MD/PhDs) with a 2-year research experience consisting of a broad focus on the basic molecular mechanisms of drug action and/or exploration of a variety of engineering disciplines. There is emphasis upon defining novel insights into mechanisms of drug action that can lead to development of therapeutic interventions and in applying engineering principles to create devices, model physiology and pathophysiology using mathematical and theoretical approaches, investigate biomaterials to facilitate non-invasive monitoring and generation of biometric data, etc. From a practical perspective, to achieve this overall goal, the training experience has two specific aims: i) expose the fellows to a culture of science and investigation present in the Department specifically and the campus broadly and ii) achieve competency in the allied elements of a research career, e.g. experimental design, data analyses, presentations, manuscript preparation and publication and how best to obtain research funding as well as lab management and job interview skills. Importantly, we strongly emphasize issues of collegiality and ethics in the research environment. In achieving our strong commitment to the development of the clinician scientist, our overriding mission is the training of the next generation of clinician scientists who have the foundation of knowledge and fundamental tools coupled with the passion and commitment to affect translational research.