Novel Group Parent Training Program for Anorexia Nervosa

描述（由候选人提供）：由Cynthia Bulik博士赞助的Nancy Zucker博士获得的以患者为导向的研究指导K23奖，描述了在饮食失调治疗发展领域的一个严格的五年培训计划，最初是针对神经性厌食症。神经性厌食症仍然是精神疾病中死亡率最高的疾病之一，然而治疗这种疾病的最有效方式仍在争论中。该培训项目的完成将使Zucker博士能够将在其他儿童疾病管理中有效的治疗模式应用于患有饮食失调症的青少年及其家庭。她将在儿童和青少年认知发展、儿童和家庭治疗方法以及研究设计方面接受进一步的高级培训。她将利用这一先进的指导，进一步开发和试点一个管理神经性厌食症的团体家长培训计划。本建议的具体目的是：1)检验一组家长培训方案对青少年饮食失调症状的初步效果；2)检查已报道的影响治疗结果的父母变量的变化，3)检查家庭功能的变化，以及4)检查干预的治疗可接受性。该干预结合了行为矫正和辩证行为治疗的技巧，同时针对已报道的神经性厌食症青少年家庭中的父母变量。扎克博士将进行两阶段的研究设计。第一阶段将包括焦点小组，由祖克博士之前主持过的家长培训小组的成员组成。第一阶段的结果将用于改进干预措施。然后，她将对改进后的干预进行试点，前后随机设计，以评估第2阶段的初步疗效。这一初步试验将进一步加强该计划，确定最适合集体父母培训模式的人群，探索潜在的行动机制，并强调进一步发展治疗的其他参与者的需求。该提案的试点数据将使她能够通过R01机制申请资助，从而对干预进行更系统的研究。因此，课程作业、培训研讨会和指导研究经验将使Zucker博士能够将治疗另类儿童疾病的有效方法与认知发展方面的高级培训相结合，从而设计出治疗青少年饮食失调的方法。

DESCRIPTION (provided by candidate): This mentored K23 award in patient-oriented research for Dr. Nancy Zucker, sponsored by Dr. Cynthia Bulik, describes a rigorous five year training program in the area of treatment development for eating disorders, initially for anorexia nervosa. Anorexia nervosa continues to have one of the highest mortality rates among psychiatric disorders, yet the most efficacious manner in which to treat this disorder continues to be debated. Completion of this training program will allow Dr. Zucker to adapt treatment models that have been effective in the management of other childhood disorders to adolescents with eating disorders and their families. She will receive further advanced training in child and adolescent cognitive development, child and family treatment approaches, and research design. She will use this advanced instruction to further develop and pilot a group parent training program for the management of anorexia nervosa. The specific aims of this proposal are: 1) to examine the preliminary efficacy of a group parent-training program on adolescent eating disorder symptoms; 2) to examine changes in parent variables that have been reported to impact treatment outcome, 3) to examine changes in family functioning, and 4) to examine the treatment acceptability of the intervention. The intervention combines skills in behavior modification and dialectical behavior therapy while targeting parent variables that have been reported in families of adolescents with anorexia nervosa. Dr. Zucker will conduct a two-stage research design. Phase 1 will consist of focus groups comprised of members of parent training groups that Dr. Zucker has previously conducted. Results from Phase I will be used to improve the intervention. She will then subject the improved intervention to a pilot, pre-post, randomized design to assess preliminary efficacy in Phase 2. This initial trial will lead to further enhancements of the program, will define the populations most suited to a group parent-training model, will permit exploration of potential mechanisms of action, and will highlight additional participant needs for further treatment development. Pilot data from this proposal will place her in a position to apply for funding via the R01 mechanism to subject the intervention to more systematic study. Thus, the coursework, training workshops, and mentored research experiences will allow Dr. Zucker to combine effective approaches for alternative childhood disorders with advanced training in cognitive development to design approaches for the treatment of adolescent eating disorders.