Cognitive-Behavioral Therapy for Pathological Gambling

描述(由候选人提供)：病理性赌博是一种相对常见的疾病，其特征是持续和反复出现的赌博行为适应不良模式。病态赌博与严重的个人痛苦以及功能障碍和犯罪行为的高比率有关。尽管它对公共卫生具有重要意义，但几乎没有得到实证调查。 在这份以患者为导向的研究职业发展奖(K-23)的申请书中，我提出了一个有组织的培训和监督研究计划，重点是病理性赌博。虽然我有现象学和精神咽喉学治疗这种疾病的背景，但我需要在以下领域进行额外的培训：1)基于证据的心理治疗，特别是认知行为治疗和动机访谈；2)干预研究的设计和方法；3)生物统计学和负责任的研究行为。这一培训将与一个研究项目相结合，在该项目中，我建议将认知行为疗法和动机访谈应用于病理性赌博的治疗，并在一项对照研究中对这种心理社会干预进行试点测试，该研究涉及68名随机接受这种干预或转介给匿名赌徒的受试者。这个项目的发现将导致R-01在K-23奖的第四年期间应用，将认知行为疗法与动机访谈与病理性赌博中的药物疗法进行比较。 这一奖项将为我提供必要的背景知识，以进一步研究病理性赌博的治疗，并为独立的以病人为导向的研究生涯提供培训。

DESCRIPTION (provided by candidate): Pathological gambling is a relatively common disorder characterized by persistent and recurrent maladaptive patterns of gambling behavior. Pathological gambling is associated with significant personal distress and high rates of both functional impairment and criminal behavior. Despite its public health significance, it has received little empirical investigation. In this application for a Mentored Patient-Oriented Research Career Development Award (K-23), I have proposed an organized program of training and supervised research focusing on pathological gambling. While have a background in the phenomenology and psychopharmaoclogical treatment of this disorder, I require additional training in the following areas: 1) evidence-based psychotherapy, specifically cognitive-behavioral therapy and motivational interviewing; 2) intervention study design and methodology; and 3) biostatistics and the responsible conduct of research. This training will be integrated with a research project in which I propose to adapt cognitive-behavioral therapy and motivational interviewing to the treatment of pathological gambling and pilot test this psychosocial intervention in a controlled study involving sixty-eight subjects randomized to this intervention or referral to Gamblers Anonymous. Findings from this project will lead to an R-01 application during year 4 of the K-23 Award comparing cognitive-behavioral therapy with motivational interviewing to pharmacotherapy in pathological gambling. This award would provide me with the necessary background for further studies in the treatment of pathological gambling and the training for an independent patient-oriented research career.