Patients, Clincs, and Systems: Screening for Alcohol Use

患者、诊所和系统：酒精使用筛查

• 批准号: 7490544
• 负责人: GRACE CHANG
• 金额: $ 15.42万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-24 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7490544
• 关键词: Achievement; Address; Adolescent; Adult; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Americas; Attention; Award; Boston; Caring; Clinical; Clinical Research; Clinical Trials; Condition; Developed Countries; Developing Countries; Development; Discipline of obstetrics; Disease; Drug usage; Education; Goals; Health; Hospitals; Individual; Maternal Age; Mentors; Midcareer Investigator Award in Patient-Oriented Research; Modification; Patient currently pregnant; Patients; Pediatric Hospitals; Philosophy; Pilot Projects; Pregnancy; Pregnancy in Adolescence; Prenatal Nutrition; Public Health; Purpose; Randomized; Rate; Reproductive Health Services; Research; Research Personnel; Review Committee; Risk; Risk Behaviors; Risk Reduction; Running; Screening procedure; Sex Behavior; Site; System; Teenagers; Testing; United States; Unplanned pregnancy; Woman; Women' s Health; adolescent substance use; alcohol research; drinking; early /brief intervention /therapy; instrument; interest; motivational intervention; next generation; nutrition education; patient oriented; patient oriented research; pregnant teen; programs; social; teacher; therapy design; young adult

This revised Competitive Renewal for the Midcareer Investigator Award in Patient-Oriented Research is being submitted to allow me to consolidate and extend the achievements realized with the first award. As requested by the Review Committee, more information about my mentoring philosophy and mentees is included. A renewal would support my goals to make a significant contribution to patient-oriented alcohol research with a particular focus on women's health, and to continue as a teacher of the next generation of clinical researchers. In mentoring, I would like to continue my otherwise unfunded individual mentoring activities, while also leading the development of a hospital-wide, interdisciplinary mentoring program as a core component of the Center for Clinical Investigation (CCI), where I am Director of Education. In patient- oriented research, my proposed project, "Identification and Modification of Alcohol and Substance Use by Pregnant Adolescents," will not only synthesize several fruitful lines of previous clinical research in the identification and reduction of risk drinking in pregnancy, and motivational interventions in reducing adolescent substance use, but also address the needs of a particularly vulnerable group. The development of a pilot study and eventual clinical trial will provide ample opportunities for junior investigators to participate. The rate of adolescent pregnancy in America is the highest among developed nations, with approximately 1 million teenagers becoming pregnant every year. Most of these adolescent pregnancies are unplanned, and tend to be recognized later than adult pregnancies. Adolescent health risk behaviors such as substance use and sexual activity cluster together, componding the biologic risk inherent in young maternal age and the adverse social consequences of adolescent pregnancy. The study's purpose is twofold: 1) to evaluate the CRAFFT alcohol and drug use screening instrument in pregnant adolescents, and 2) to test the hypothesis that those subjects receiving the motivational intervention will demonstrate greater reductions in alcohol and substance use than those randomized to the attention control condition, consisting of prenatal nutrition education. The proposed study site is the Young Adult Reproductive Health Service, run by the Brigham and Women's Hospital in conjunction with Children's Hospital for the past two decades, and serves 200 new patients annually.

此次修订后的以患者为导向的研究中的职业生涯中期研究者奖竞争性更新是 提交该奖项是为了让我能够巩固和扩展第一个奖项所取得的成就。作为 应审查委员会的要求，有关我的指导理念和受指导者的更多信息是 包括。续约将支持我的目标，即为以患者为中心的酒精事业做出重大贡献 特别关注女性健康的研究，并继续担任下一代的教师 临床研究人员。在指导方面，我想继续我原本没有资金的个人指导 活动，同时还领导制定全院范围内的跨学科指导计划，作为 临床研究中心 (CCI) 的核心组成部分，我是该中心的教育主任。在病人身上—— 面向研究，我提出的项目“酒精和物质使用的识别和修改” 怀孕青少年”不仅将综合以前临床研究的几条富有成效的路线 识别和减少妊娠期饮酒风险，并采取动机干预措施来减少 青少年药物滥用，同时也满足特别弱势群体的需求。发展历程 试点研究和最终的临床试验将为初级研究人员提供充足的机会 参加。美国青少年怀孕率是发达国家中最高的 每年约有 100 万青少年怀孕。大多数青少年怀孕是 计划外的，并且往往晚于成人怀孕才被认识到。青少年健康风险行为，例如 由于物质使用和性活动聚集在一起，加剧了年轻人固有的生物风险 母亲年龄和青少年怀孕的不良社会后果。该研究的目的是 双重目的：1) 评估 CRAFFT 酒精和药物使用筛查仪对怀孕青少年的影响，以及 2）检验接受动机干预的受试者将表现出更大的假设 与随机分配到注意力控制条件的组相比，酒精和药物使用的减少，包括 产前营养教育。拟议的研究地点是年轻成人生殖健康服务中心，由 在过去的二十年中，由布莱根妇女医院与儿童医院联合开展，以及 每年为 200 名新患者提供服务。