Global Network for Women's and Children's Health

全球妇女儿童健康网络

基本信息

项目摘要

DESCRIPTION (provided by applicant): We propose to develop a Global Network for Women's and Children's Health Research site in Eldoret, Kenya. This East African site will be a joint partnership between Indiana University and Moi University School of Medicine, one of two medical schools in Kenya. The 17 year partnership of Moi University and Indiana University will bring unique strengths to the Global Network. These include an established administrative, scientific, and collegial relationship between the institutions, an extensive research infrastructure that includes an established network of rural health centers from which to draw subjects, a well functioning Kenyan Institutional Review Board with a OHRP Assurance number, and an established expanding coverage of subjects by an electronic medical record. The Senior Foreign Investigator is Dean of the Medical School, and has well established relationships with high level Ministry of Health personnel. A large number of other Moi University investigators with expertise in Obstetrics, Public Health, Nutrition, Epidemiology, and Behavioral Sciences are also eager to join the Global Network. US based expertise is also present in Obstetrics, Biostatistics, and Bioethics. We propose to the Network a cluster randomized protocol evaluating the efficacy of both Community Mobilization for the use of a Safe Water System (SWS) and for zinc supplementation in partially weaned infants less than 6 months of age. The SWS includes specially designed narrow neck water storage containers and point of use home chlorination using dilute sodium hypochlorite. Hypotheses to be tested are that 1.) Community Mobilization will result in sustained, consistent use of point of use water treatment 2.) This will lead to a decreased incidence of diarrhea in less than 6 month old infants. 3.) Zinc supplementation beginning at partial weaning will lead to a further decrease in the incidence of diarrhea in these infants. 4.) Growth will be improved and failure to thrive decreased in experimental groups. 5.) All cause mortality in >6 month old infants will be decreased in experimental groups. If efficacy is shown, these are highly sustainable interventions that will improve the health and well being of vulnerable infants.
描述(由申请人提供):我们建议在肯尼亚埃尔多雷特建立一个全球妇女和儿童健康研究网络。这个东非网站将是印第安纳州大学和莫伊大学医学院之间的联合伙伴关系,莫伊大学医学院是肯尼亚的两所医学院之一。莫伊大学和印第安纳州大学17年的合作伙伴关系将为全球网络带来独特的优势。这些包括机构之间建立的行政,科学和学院关系,广泛的研究基础设施,包括一个建立的农村卫生中心网络,从中抽取受试者,一个运作良好的肯尼亚机构审查委员会,具有OHRP保证编号,以及通过电子病历建立的受试者覆盖范围扩大。高级外国研究员是医学院院长,与卫生部高级人员建立了良好的关系。莫伊大学的其他大量研究人员在产科、公共卫生、营养、流行病学和行为科学方面都有专长,他们也渴望加入全球网络。美国的专业知识也存在于产科,生物统计学和生物伦理学。我们建议网络的集群随机协议,评估社区动员使用安全供水系统(SWS)和锌补充剂在部分断奶婴儿不到6个月的年龄。SWS包括专门设计的窄颈储水容器和使用点家庭氯化使用稀次氯酸钠。待检验的假设为:1.)社区动员将导致持续、一致地使用使用点水处理2。这将导致6个月以下婴儿腹泻的发病率降低。3.)第三章在部分断奶时开始补充锌将导致这些婴儿腹泻发病率的进一步降低。4.)在实验组中,生长将得到改善,并且不能茁壮成长的情况减少。5.)实验组6个月以上婴儿的全因死亡率将降低。如果效果得到证明,这些干预措施将是高度可持续的,将改善脆弱婴儿的健康和福祉。

项目成果

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{{ truncateString('EDWARD A. LIECHTY', 18)}}的其他基金

Global Network for Women's and Children's Health Research
全球妇女和儿童健康研究网络
  • 批准号:
    9063169
  • 财政年份:
    2013
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health Research
全球妇女和儿童健康研究网络
  • 批准号:
    8517888
  • 财政年份:
    2013
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health Research
全球妇女和儿童健康研究网络
  • 批准号:
    8820926
  • 财政年份:
    2013
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health Research
全球妇女和儿童健康研究网络
  • 批准号:
    8842155
  • 财政年份:
    2013
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health Research
全球妇女和儿童健康研究网络
  • 批准号:
    9273560
  • 财政年份:
    2013
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health Research
全球妇女和儿童健康研究网络
  • 批准号:
    8727729
  • 财政年份:
    2013
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health
全球妇女儿童健康网络
  • 批准号:
    8400459
  • 财政年份:
    2008
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health
全球妇女儿童健康网络
  • 批准号:
    7641069
  • 财政年份:
    2008
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health
全球妇女儿童健康网络
  • 批准号:
    8069138
  • 财政年份:
    2008
  • 资助金额:
    $ 62.02万
  • 项目类别:
Global Network for Women's and Children's Health
全球妇女儿童健康网络
  • 批准号:
    8226891
  • 财政年份:
    2008
  • 资助金额:
    $ 62.02万
  • 项目类别:
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