Randomized Trial of Tapas Acupressure for Weight Loss Maintenance

塔帕斯穴位按摩维持减肥的随机试验

• 批准号: 7491249
• 负责人: CHARLES R ELDER
• 金额: $ 68.12万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7491249
• 关键词: Acupressure; Acupuncture Points; Adult; Affect; American; Behavior Therapy; Behavioral; Belief; Body Weight Changes; Body Weight decreased; Cardiovascular Diseases; Caring; Cessation of life; Characteristics; Chinese People; Communities; Complementary and alternative medicine; Control Groups; Control Locus; Diet; Educational process of instructing; Effectiveness of Interventions; Eligibility Determination; Epidemic; Funding; Group Meetings; Guidelines; Health; Home environment; Hour; Hyperlipidemia; Hypertension; Image; Instruction; Intervention; Maintenance; Malignant Neoplasms; Managed Care; Measures; Mediating; Mediator of activation protein; Medicine; Mental Depression; Methodology; Mind; Mind-Body Intervention; Monitor; National Center for Complementary and Alternative Medicine; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Outcome; Overweight; Participant; Patients; Physical activity; Primary Health Care; Procedures; Psyche structure; Psychosocial Stress; Public Health; Quality of life; Questionnaires; Randomized; Randomized Clinical Trials; Randomized Controlled Clinical Trials; Recruitment Activity; Research; Risk Factors; Standards of Weights and Measures; Statistically Significant; Stress; Support Groups; Techniques; Testing; United States; Week; Weight Gain; Weight maintenance regimen; Yin; base; cardiovascular disorder risk; cost; experience; follow-up; food craving; pilot trial; pressure; prevent; psychosocial; satisfaction; self esteem; tool; weight loss intervention; weight maintenance

DESCRIPTION (provided by applicant): Overweight and obesity are the second leading cause of preventable death, primarily through effects on cardiovascular disease (CVD) risk factors and cancer. Despite inclusion of weight control as a core component of treatment guidelines for hypertension, hyperlipidemia, and type 2 diabetes, the obesity epidemic continues to grow, affecting over 100 million Americans. A major factor contributing to this escalating epidemic is the disappointingly common phenomenon of re-gain of weight after successful initial weight loss. We recently completed a pilot trial assessing the feasibility and impact of two mind-body interventions from the Chinese Medicine tradition for weight loss maintenance in overweight and obese adults. Results of the pilot suggested that the Tapas Acupressure Technique (TAT) warrants further research as a potential tool for weight loss maintenance. The TAT procedure combines self-acupressure administration with specific mental focus. Patients are taught how to first identify counterproductive beliefs and actions, focus on those images while applying pressure to acupoints GB21, BL1, and Yin Tang, and then transition to a focus on positive images. We now propose a randomized clinical trial evaluating the efficacy of TAT compared to a usual care control support group for the primary outcome of weight loss maintenance. We will recruit obese and overweight adults from community and managed care settings. Those meeting eligibility requirements will be assigned to a 20-week intensive group-based behavioral weight loss intervention. Approximately 288 patients who upon completion of the weight loss component meet threshold weight loss criteria will then be randomly assigned to either TAT instruction or the facilitated support group control. Patients in both groups will attend a total of 8 group meetings over 6 months for a total of 13 contact hours, and patients in the TAT group will be advised to practice the technique at home. Participants will be weighed at baseline, randomization, and then again at 3, 6, 9, and 12 months. Questionnaires will also be administered at baseline and one year follow-up toward measuring both secondary outcomes (quality of life and psychosocial function) and potential mediators (diet, physical activity, food cravings, psychosocial stress). Statistically significant improvements in weight loss maintenance in the proposed trial could indicate inclusion of TAT as a standard weight loss maintenance intervention within the conventional care setting. The relevance of this research to public health is: Overweight and obesity are the second leading cause of preventable death, primarily through effects on cardiovascular disease (CVD) risk factors and cancer. Despite inclusion of weight control as a core component of treatment guidelines for hypertension, hyperlipidemia, and type 2 diabetes, the obesity epidemic continues to grow, affecting over 100 million Americans.

描述（由申请人提供）：超重和肥胖是可预防死亡的第二主要原因，主要是通过对心血管疾病（CVD）危险因素和癌症的影响。尽管将体重控制纳入高血压，高脂血症和2型糖尿病的治疗指南的核心组成部分，但肥胖流行仍在继续增长，影响了1亿多美国人。导致这种不断升级的流行病的一个主要因素是成功初步体重减轻后重获得体重的令人失望的常见现象。我们最近完成了一项试点试验，评估了中医传统两种思维方式干预措施对超重和肥胖成年人减肥的可行性和影响。飞行员的结果表明，小吃穴技术（TAT）值得进一步研究，作为维持减肥的潜在工具。 TAT程序将自任务给药与特定的心理重点相结合。教患者如何首先识别适得其反的信念和动作，专注于这些图像，同时将压力施加压力GB21，BL1和Yin Tang，然后过渡到侧重于正面图像。现在，我们提出了一项随机临床试验，该试验评估了TAT与通常的护理控制支持组相比，以减肥的主要结果。我们将从社区和托管护理环境中招募肥胖和超重成年人。那些满足资格要求的人将被分配给20周的基于集体的集体行为减肥干预措施。大约有288例完成减肥成分后，符合阈值减肥标准的患者将被随机分配给TAT指令或促进的支持组控制。两组的患者将在6个月内总共参加8个小组会议，总共13个接触小时，并建议TAT组的患者在家中练习该技术。参与者将在基线，随机分组，然后在3、6、9和12个月再次称重。问卷还将在基线和一年的随访中进行，以衡量次要结果（生活质量和社会心理功能）和潜在的介体（饮食，体育锻炼，食物渴望，社会心理压力）。在拟议的试验中，减肥维持的统计显着改善可能表明将TAT作为标准的体重减轻维持干预措施包括在常规护理环境中。这项研究与公共卫生的相关性是：超重和肥胖是可预防死亡的第二主要原因，主要是通过对心血管疾病（CVD）危险因素和癌症的影响。尽管将体重控制纳入高血压，高脂血症和2型糖尿病的治疗指南的核心组成部分，但肥胖流行仍在继续增长，影响了1亿多美国人。