Pilot of Two CAM Tratments for Maintenance Wt Loss

两种 CAM 处理维护重量损失的试验

• 批准号: 6792588
• 负责人: CHARLES R ELDER
• 金额: $ 19.75万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-15 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6792588
• 关键词: acupuncture /acupressure; alternative medicine; behavior therapy; behavioral /social science research tag; body physical activity; clinical research; clinical trials; diet; disease /disorder prevention /control; group therapy; human subject; human therapy evaluation; longitudinal human study; nutrient intake activity; obesity; outcomes research; quality of life; questionnaires; self care; social psychology; social support network; weight control; weight loss

DESCRIPTION (provided by applicant): The prevalence of obesity is at epidemic proportions, 60% of US adults are overweight or obese. Obesity contributes to chronic diseases-diabetes, CVD, hypertension, diabetes, cancer and osteoarthritis and to escalating health care costs. Weight loss can have a substantial impact on reducing these conditions. Substantial efforts have been made in developing effective short-term wt. loss programs using behavioral treatments. However, long-term maintenance of wt. loss continues to be problematic - many individuals regain the wt. lost within a year. Innovative intervention options are critically needed to help people successfully maintain weight loss and to fight the obesity epidemic. Complementary and alternative medicine (CAM) approaches - mind-body, energy healing, and Traditional Chinese Medicine (TCM) approaches - may hold great promise for helping improve the maintenance of wt. loss. Despite long historical use, significant anecdotal and case report information on benefits and efficacy, plausible biologic mechanisms for action and great consumer interest, there is little data available on the evaluation of these CAM therapies for wt. maintenance or wt. loss. The goal of this study is to pilot test in a group of overweight-obese individuals the feasibility and acceptability and indications of efficacy of two CAM treatments, qigong, and acupressure-TAT, for improving long term maintenance of wt. loss. The design is a randomized, controlled 3-arm study: 1) Control, 2) qigong maintenance and 3) Acupressure-TAT maintenance, with 30 participants per group. All participants receive a standard 12-week behavioral wt. loss program. Following this, participants are randomized to receive the maintenance interventions and are followed for 6 months. Measurements occur at screening, baseline, and 12, and 24 post-randomization. Outcomes include: wt. change, diet, physical activity, self-reported use of the maintenance techniques, acceptability and satisfaction with the approaches as well as a variety of psychosocial parameters that may be mediators or moderated by the intervention (QOL, perceived stress, etc.). Information from this study will be used to develop a larger randomized trial to evaluate different maintenance approaches to improve long-term maintenance of wt. loss.

描述（由申请人提供）：肥胖症的流行率是流行病的，美国60％的成年人超重或肥胖。肥胖有助于慢性疾病糖尿病，CVD，高血压，糖尿病，癌症和骨关节炎，并升级医疗费用。减肥可能会对减少这些条件产生重大影响。在开发有效的短期WT方面已做出了巨大的努力。使用行为治疗的损失计划。但是，WT的长期维护。损失仍然存在问题 - 许多人恢复了wt。在一年内损失。需要进行创新的干预选择，以帮助人们成功地维持体重减轻并与肥胖症患者抗争。互补和替代医学（CAM）方法 - 思维体，能量康复和中医（TCM）方法 - 可能会有很大的希望，可以帮助改善维持wt的维持。损失。尽管历史悠久，大量的轶事和案例报告信息有关收益和功效，可行的生物学机制以及极大的消费者兴趣，但对于WT评估这些CAM疗法的数据很少。维护或wt。损失。这项研究的目的是在一组超重肥胖个体中进行试验测试，以提高两种CAM治疗的可行性，可接受性和指示，即气功和尖端 - tAT，以改善WT的长期维持。损失。该设计是一项随机，受控的3臂研究：1）控制，2）气功维护和3）穴位 - tAT维护，每组30名参与者。所有参与者都将获得标准的12周行为wt。损失计划。之后，参与者被随机接受维护干预措施，并遵循6个月。测量在筛选，基线和12和24个随机后进行。结果包括：wt。变化，饮食，体育锻炼，自我报告使用维护技术，可接受性和满足方法以及可能是介体或通过干预措施进行调解的各种社会心理参数（QOL，感知的压力等）。这项研究的信息将用于开发更大的随机试验，以评估不同的维护方法，以改善WT的长期维护。损失。