VIROLOGY CORE

北卡罗来纳州大学CFAR核心D病毒学实验室;主任：Susan A Fiscus，博士，教授 副主任：Leslie Petch，Ph.D. 病毒学核心实验室为CFAR提供实验室支持，并促进基本的艾滋病研究 来自北卡罗来纳州大学（University of North Carolina）、国际家庭健康组织（Family Health International）和研究中心（Research 三角研究所（RTI）。具体来说，病毒学核心实验室是一组已建立的研究人员， 非常有经验的技术人员，他们在最先进的临床和分子水平方面提供高水平的专业知识 用于培养、定量和测序HIV的测定。此外，我们还提供机构基础设施， 作为与免疫学和临床核心结合的生物样本的储存库， 目前CDC-USPHS允许从国外进口HIV+标本，以及BSL-3设施。的 核心D实验室在当地为六个CFAR工作组提供科学领导，在全国范围内为AACTG提供科学领导， PACTG、HPTN和ATN，以及国际上的CIPRA和CDC-GAP。我们鼓励合作， 跨学科和翻译研究，帮助众多CFAR调查人员从各种各样的 加强马拉维、刚果的能力， 南非等;促进科学交流，为107份摘要和127份同行评审论文做出了贡献 在过去五年中，为numeorus foreign和 国内调查员和研究协调员;通过以下方式促进技术转让和开发： 促进生物技术和Gen-Probe、CavidiTech和Perkin-Elmer之间的科学合作。 过去五年的主要成就是在急性艾滋病毒感染和预防母婴传播（CDC-母乳喂养）领域 和营养研究，CDC-全球艾滋病项目，NVAZ）。支持的其他主要研究 该报告包括：成人艾滋病临床试验小组、马拉维艾滋病毒预防试验股、Fogarty国际培训赠款和分区域艾滋病毒赠款。

University of North Carolina CFAR Core D Virology Laboratory; Director: Susan A Fiscus, Ph.D., Professor of Microbiology & Immunology; Associate Director: Leslie Petch, Ph.D. The Virology Core Laboratory provides laboratory support and facilitates basic AIDS research to CFAR investigators at the University of North Carolina (UNC), Family Health International (FHI), and Research Triangle Institute (RTI). Specifically the Virology Core Laboratory is a group of established investigators and very experienced technologists who provide a high level of expertise in state of the art clinical and molecular assays for culturing, quantitating, and sequencing HIV. In addition we provide institutional infrastructure such as a repository for storage of biological specimens in conjuction with the Immunology and Clincial Cores, current CDC-USPHS permit for importing HIV+ specimens from foreign countries, and a BSL-3 facility. The UNC Core D Lab provides scientific leadership locally to six CFAR working groups, nationally to the AACTG, PACTG, HPTN, and ATN, and internationally to CIPRA and the CDC-GAP. We stimulate collaboration in interdisciplinary and translational research by helping numerous CFAR investigators from a wide variety of UNC CFAR departments or institutions; strengthen capacity in Malawi, Democratic Republic of Congo, and South Africa, among others; foster scientific communication, contributing to 107 abstracts and 127 peerreviewed manuscripts over the past five years; sponsor training opportunities to numeorus foreign and domestic investigators and study coodinators; and facilitate technology transfer and development through promotion of scientific collaborations between UNC and Gen-Probe, CavidiTech, and Perkin-Elmer. Major accomplishments over the past five years have been in the fields of acute HIV infection and prevention of mother to child transmission (CDC-Breastfeeding and Nutrition Study, CDC-Global AIDS Project, NVAZ). Other major studies that are supported the UNC CFAR include: Adult AIDS Clinical Trials Group, HIV Prevention Trial Unit in Malawi, Fogarty international training grant, and grants dealing with HIV in compartments.