VIROLOGY CORE

北卡罗来纳大学CFAR核心D病毒学实验室；主任：Susan A Fiscus，博士，教授 微生物学和免疫学系；副主任：Leslie Petch，博士。 病毒学核心实验室为CFAR提供实验室支持和促进艾滋病基础研究 北卡罗来纳大学(UNC)、国际家庭健康组织(FHI)和研究中心的研究人员 三角研究所(RTI)。具体地说，病毒学核心实验室是一组老牌的研究人员和 经验丰富的技术专家，提供最先进的临床和分子方面的高水平专业知识 HIV培养、定量和测序的分析方法。此外，我们还提供机构基础设施，如 作为与免疫学和临床核心相结合的生物标本储存库， 目前CDC-USPHS允许从外国进口艾滋病毒样本，以及BSL-3设施。这个 北卡罗来纳大学核心D实验室在当地为CFAR的六个工作组提供科学领导，在全国为AACTG提供科学领导， PACTG、HPTN和ATN，以及国际上的CIPRA和CDC-GAP。我们在以下方面促进合作 通过帮助来自各种不同领域的众多CFAR调查人员进行跨学科和转化性研究 联合国儿童基金会各部门或机构；加强马拉维、刚果民主共和国和 南非等；促进科学交流，贡献了107篇摘要和127篇同行评议 过去五年的手稿；赞助培训机会给Numorus国外和 国内调查员和研究辅助者；并通过以下方式促进技术转让和开发 促进北卡罗来纳大学与Gen-Probe、CavidiTech和Perkin-Elmer之间的科学合作。 在过去五年中，在急性艾滋病毒感染和预防母婴传播(CDC-母乳喂养)领域取得了重大成就 和营养研究，疾控中心-全球艾滋病项目，NVAZ)。其他得到支持的主要研究 北卡罗来纳州CFAR包括：成人艾滋病临床试验小组、马拉维艾滋病毒预防试验股、Fogarty国际培训补助金和在隔间处理艾滋病毒的补助金。

University of North Carolina CFAR Core D Virology Laboratory; Director: Susan A Fiscus, Ph.D., Professor of Microbiology & Immunology; Associate Director: Leslie Petch, Ph.D. The Virology Core Laboratory provides laboratory support and facilitates basic AIDS research to CFAR investigators at the University of North Carolina (UNC), Family Health International (FHI), and Research Triangle Institute (RTI). Specifically the Virology Core Laboratory is a group of established investigators and very experienced technologists who provide a high level of expertise in state of the art clinical and molecular assays for culturing, quantitating, and sequencing HIV. In addition we provide institutional infrastructure such as a repository for storage of biological specimens in conjuction with the Immunology and Clincial Cores, current CDC-USPHS permit for importing HIV+ specimens from foreign countries, and a BSL-3 facility. The UNC Core D Lab provides scientific leadership locally to six CFAR working groups, nationally to the AACTG, PACTG, HPTN, and ATN, and internationally to CIPRA and the CDC-GAP. We stimulate collaboration in interdisciplinary and translational research by helping numerous CFAR investigators from a wide variety of UNC CFAR departments or institutions; strengthen capacity in Malawi, Democratic Republic of Congo, and South Africa, among others; foster scientific communication, contributing to 107 abstracts and 127 peerreviewed manuscripts over the past five years; sponsor training opportunities to numeorus foreign and domestic investigators and study coodinators; and facilitate technology transfer and development through promotion of scientific collaborations between UNC and Gen-Probe, CavidiTech, and Perkin-Elmer. Major accomplishments over the past five years have been in the fields of acute HIV infection and prevention of mother to child transmission (CDC-Breastfeeding and Nutrition Study, CDC-Global AIDS Project, NVAZ). Other major studies that are supported the UNC CFAR include: Adult AIDS Clinical Trials Group, HIV Prevention Trial Unit in Malawi, Fogarty international training grant, and grants dealing with HIV in compartments.