CORE--EXPOSURE ANALYSIS AND HEALTH EFFECTS

描述（由申请人提供）：该核心由来自五个系和三个学院的16名成员组成：罗格斯大学，umdnj -罗伯特伍德约翰逊医学院和umdnj -公共卫生学院。这些成员代表了广泛的物理、生物医学和工程科学家，他们有一个共同的目标，即测量和模拟人类和动物接触环境毒物的情况，并研究这些接触对儿童和某些成年人健康的影响。目标是：a)在高风险人群中进行环境暴露和环境健康研究

Description (provided by applicant): This Core comprises 16 members from five departments and three schools: Rutgers University, UMDNJ-Robert Wood Johnson Medical School and the UMDNJ-School of Public Health. The members represent a broad spectrum of physical, biomedical and engineering scientists sharing a common goal of measuring and modeling exposure of humans and animals to environmental toxicants and in examining the effects of these exposures on health of children and selected adult populations. The goals are, a) to conduct environmental exposure and environmental health studies among high risk children and adult populations; b) to conduct controlled exposure studies to determine physiological and psychological predictors and outcomes of ambient level exposures; c) to develop exposure?dose models from the populations to the tissue level; d) to develop and employ physical, chemical and biological markers of exposure and/or effect; and e) to integrate the results of exposure characterization and estimation into the development of basic toxicological research. There are three themes in this core. They are, Exposures of Children and High-Risk Adult Populations, Effects of Controlled Exposures, and Source-to-Dose Modeling.