Core Grant for Vision Research

视觉研究核心资助

• 批准号: 7285174
• 负责人: CHRISTOPHER W TYLER
• 金额: $ 68.41万
• 依托单位: SMITH-KETTLEWELL EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7285174
• 关键词: Aging; Area; Binocular Vision; Biophysics; Brain imaging; Cancer Center Support Grant; Clinical; Collaborations; Communication; Communities; Computers; Development; Disabled Persons; Electronics; Engineering Psychology; Equipment Design; Explosion; Eye; Functional Magnetic Resonance Imaging; Funding; Grant; Head; Health Services Research; Image; Imaging Techniques; Individual; Laboratories; Magnetic Resonance Imaging; Maintenance; Medical; Numbers; Ophthalmology; Optometry; Photoreceptors; Postdoctoral Fellow; Preparation; Primates; Principal Investigator; Process; Productivity; Research; Research Institute; Resource Sharing; Resources; Scientist; Services; Standards of Weights and Measures; Technical Expertise; Techniques; Technology; Training; Vision; Vision Disorders; Vision research; Visual Pathways; Visual system structure; Work; animal resource; experience; interest; neurophysiology; object recognition; oculomotor; optical imaging

DESCRIPTION (provided by applicant): Research at the Smith-Kettlewell Eye Research Institute (SKERI) is focused on clinical and basic studies in vision and disorders of the visual system. Smith-Kettlewell scientists have training from diverse medical and scientific backgrounds: ophthalmology, neurophysiology, experimental psychology, engineering, optometry and biophysics. Their main topics of study are oculomotor processing, dynamics of binocular vision, cortical organization and development of the visual pathways, vision in the aging eye, analysis of photoreceptor function, object recognition and computational vision in the service of the disabled. Particular emphasis has been laid on the application of modern imaging techniques to these problems, including the diverse techniques of multifocal ERG, MRI, fMRI, DTI, whole-head VEP, whole-head MEG, optical imaging of cortex, and SLO imaging. For the past three decades, the NEI Core Grant has formed the central component of its most important shared research services, chiefly computer communication and resources, and electronic equipment design and maintenance. Given the moderate scale of the Smith-Kettlewell group, the proximity of the scientists, and their common research interests, collaboration among scientists is standard practice. Principal Investigators share resources with little difficulty. The technical expertise of our Computer Services and Electronics Hardware modules greatly benefits the rapid development of new research agendas - a tremendous advantage for new principal investigators and postdoctoral fellows, and a major factor in our high productivity. In recent years, the vision community has experienced an explosion of research in the area of brain imaging. Smith-Kettlewell has kept step with this technology and has several grants currently funded, with many other projects in the works. The addition of a Brain Imaging Module will provide valuable support resources in the areas of MRI, fMRI, whole-head VEP, DTI, and whole-head MEG imaging that are impractical to provide on individual grants. In addition, a Laboratory Animal Resources Module will provide the technical support and resources necessary to continue the high-level research conducted on the alert behaving primate preparation conducted by a number of groups at Smith-Kettlewell.

描述（由申请人提供）： 史密斯-凯特尔韦尔眼科研究所（SKERI）的研究重点是视觉和视觉系统疾病的临床和基础研究。Smith-Kettlewell的科学家们接受了来自不同医学和科学背景的培训：眼科学，神经生理学，实验心理学，工程学，验光学和生物物理学。他们的主要研究课题是视觉处理，双眼视觉的动力学，视觉通路的皮层组织和发展，衰老眼睛的视觉，光感受器功能分析，物体识别和为残疾人服务的计算视觉。特别强调了现代成像技术在这些问题上的应用，包括多焦ERG、MRI、fMRI、DTI、全头VEP、全头MEG、皮质光学成像和SLO成像的各种技术。 在过去的三十年里，NEI核心补助金已经形成了其最重要的共享研究服务的核心组成部分，主要是计算机通信和资源，以及电子设备的设计和维护。考虑到史密斯-凯特韦尔小组的规模适中，科学家的接近程度以及他们共同的研究兴趣，科学家之间的合作是标准做法。 主要研究人员分享资源，没有什么困难。我们的计算机服务和电子硬件模块的技术专长极大地有利于新的研究议程的快速发展-新的主要研究人员和博士后研究员的巨大优势，以及我们的高生产力的主要因素。 近年来，视觉界在大脑成像领域经历了爆炸式的研究。史密斯-凯特尔韦尔一直在与这项技术保持同步，目前有几赠款，还有许多其他项目正在进行中。脑成像模块的增加将在MRI，fMRI，全头VEP，DTI和全头MEG成像领域提供宝贵的支持资源，这些资源在个人赠款上是不切实际的。此外，实验室动物资源模块将提供必要的技术支持和资源，以继续进行由史密斯-凯特尔韦尔的一些小组进行的关于警觉行为灵长类动物制备的高水平研究。