Pediatric Quality of Life: Is it lost in traduccion?

描述(申请人提供)：哮喘是影响儿童的最常见的慢性疾病。有人建议，为了全面了解哮喘对儿童的影响，有必要直接测量生活质量(QOL)(Juniper等人，1996年)。衡量哮喘儿童生活质量的有效概念模型将帮助提供者了解对患者生活影响最大的情况，并帮助评估不同患者护理方法的相对重要性(Wilson&Cleary，1997)。Juniper和他的同事(1996)开发了一个概念模型来衡量哮喘儿童的生活质量，即儿童哮喘生活质量问卷(PAQLQ)。这份问卷是在一个种族相同的样本中制定的，然后被翻译成包括西班牙语在内的20多种语言。首席调查员打算使用PAQLQ作为群体比较的结果衡量标准，即说英语的儿童与说西班牙语的儿童。然而，对于群体间比较的PAQLQ的测量不变性，我们知之甚少。相对较新的分析技术可用于评估测量不变性的工具，这是在总体组之间进行适当比较的必要要求。斯图尔特和那不勒斯-斯普林格(2000)指出，对像PAQLQ这样的自我报告的测量进行有效的比较，需要这些概念在不同群体中具有类似的含义。在被比较的组中，测量必须以类似的方式符合测量不变性。因此，本研究的目的是利用二手数据，使用结构方程模型和测量不变性分析来检验PAQLQ的英语和西班牙语版本的概念和测量特性。测量不变性分析涉及在两个或多个独立的人群组中测试被测结构的等价性，以确保每个组的心理测量学特性相似，因此组比较是合适的。本研究的目的如下：目的1.运用结构方程模型的验证性方法，对PAQLQ在英语和西班牙语两个版本中的结构效度进行评价。目的2.使用测量不变性分析评估PAQLQ的英语和西班牙语版本的等价性。目的3如果PAQLQ的英语和西班牙语版本之间没有实现测量不变性，那么将采取几个步骤来使用扫描电子显微镜来改进该工具，以提高其结构效度、跨人群的测量等价性，并最大限度地减少群体分析之间的偏差。当使用生活质量作为结果来获取不同群体之间的高质量护理时，研究人员和政策制定者对该工具的保真度具有信心是至关重要的。儿童哮喘生活质量问卷还没有经过测量不变性的测试，这是一种相对较新的分析技术，是进行适当的组间比较的必要要求

DESCRIPTION (provided by applicant): Asthma is the most common chronic disease affecting children. It has been suggested that to gain a full picture of the impact of asthma on children, it is necessary to make direct measurements of quality of life (QOL) (Juniper et al., 1996). A valid conceptual model to measure QOL in children living with asthma would help providers learn about conditions that have the greatest impact on patients' lives and help evaluate the relative importance of different approaches to patient care (Wilson & Cleary, 1997). Juniper and colleagues (1996) developed a conceptual model to measure QOL of children living with asthma, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). This questionnaire was developed within an ethnically homogenous sample and then translated into over 20 languages including Spanish. The Principal Investigator intends on using the PAQLQ as an outcome measure for group comparisons, English-speaking versus Spanish-speaking children. However, little is know about the measurement invariance of the PAQLQ for between population group comparisons. Relatively new analytical techniques are available to evaluate instruments for measurement invariance which is a necessary requirement for appropriate between population group comparisons. Stewart and Napoles- Springer (2000) stated that a valid comparison of self-reported measures like the PAQLQ requires that the concepts have similar meaning across groups. Measures must conform to measurement invariance in similar ways across the groups being compared. Thus the purpose of the proposed research is, using secondary data, to examine the concepts and measurement properties of the English- and Spanish-language versions of the PAQLQ using SEM and measurement invariance analysis. Measurement invariance analysis involves testing the equivalence of measured constructs in two or more independent population groups to assure that the psychometric properties are similar in each group and therefore group comparisons are appropriate. The following are the aims for this application: Aim 1. Using the confirmatory approaches of SEM evaluate the construct validity of the PAQLQ in both the English- and Spanish-language versions. Aim 2. Evaluate the equivalence of the English- and Spanish-language versions of the PAQLQ using measurement invariance analysis. Aim 3 if measurement invariance is not achieved between the English- and Spanish-language versions of the PAQLQ, then several steps will be taken using SEM to refine the instrument to improve its construct validity, measurement equivalence across populations, and to minimize bias fro between group analyses. When using quality of life as an outcome to capture quality care, between diverse groups, it is vital that researchers and policy makers have confidence in the fidelity of the instrument. The Pediatric Asthma Quality of Life Questionnaire has not been tested for measurement invariance, a relatively new analytical technique, which is a necessary requirement for appropriate between group comparisons