6th International Conference on Unstable Microsatellites and Human Disease

描述（由申请人提供）：第六届不稳定微卫星与人类疾病国际会议将重点关注需要临床医生、诊断医生、病理学家、遗传学家和分子生物学家聚集的研究领域的多学科性质。除了关注最新的科学进展外，会议的目标还包括：1)加强与微卫星扩张性疾病有关的信息的公开交流；2)促进世界范围内研究者之间开展合作研究，提高对与微卫星不稳定性有关的人类疾病的了解；3)为初级研究者提供展示其工作的机会，并与该领域更成熟的科学家进行互动。该会议在迅速分享新信息、促进科学交流、形成合作方面具有良好的记录，并已成为培训年轻科学家（研究生、博士后研究员和pi）的绝佳场所。这是关于这些突变和疾病的首次会议。以讲台或海报形式发表的论文已在《Science》、《Nature》、《Nature Genetics》、《Cell》、《Molecular Cell》、《American Journal of Human Genetics》、《Human Molecular Genetics》、《Molecular and Cellular Biology》、《Journal of Biological Chemistry》等优秀期刊发表。公共卫生相关性：第六届不稳定微卫星与人类疾病国际会议将继续侧重于了解核酸和蛋白质的重复不稳定性及其与人类疾病、遗传性疾病和其他疾病的关系方面的最新进展。自1991年首次发现这种类型的突变与疾病有关以来，已经发现至少36种不同的遗传性疾病是由这种形式的突变引起的，以及许多与遗传不稳定有关的疾病。

DESCRIPTION (provided by applicant): The Sixth International Conference on Unstable Microsatellites and Human Disease will focus on the multidisciplinary nature of the research field requiring the gathering of clinicians, diagnosticians, pathologists, geneticists and molecular biologists. In addition to focusing upon the most recent scientific advances, the goals of the meeting include: 1) To enhance the open exchange of information related to microsatellite expansion diseases; 2) To stimulate the initiation of collaborative research between investigators worldwide and to improve the understanding of human diseases related to microsatellite instability and 3) To provide junior investigators with an opportunity to present their work and to interact with more established scientists in the field. This meeting has a proven track record of rapidly sharing new information, stimulating scientific exchange, forming collaborations and has served as an excellent venue for training of young scientists (graduate students, post-doctoral fellows and PIs). This is the premier meeting on these mutations and diseases. Submitted papers that have been presented as podium or poster presentations have been published in the best journals, including Science, Nature, Nature Genetics, Cell, Molecular Cell, American Journal of Human Genetics, Human Molecular Genetics, Molecular and Cellular Biology, and Journal of Biological Chemistry. PUBLIC HEALTH RELEVANCE: The Sixth International Conference on Unstable Microsatellites and Human Disease will continue to focus upon the most recent advances in understanding repeat instability of nucleic acids and proteins and their relationship to human diseases, inherited and other. Since 1991, when this type of mutation was first associated with disease there have been at least 36 different hereditary diseases found to be caused by this form of mutation as well as numerous diseases that are associated with genetic instabilities.