Seventh International Symposium on Functional Neuroreceptor Mapping (NRM08)

描述（由申请人提供）：我们寻求NIMH和NIDA的49，000美元的支持，以主办2008年7月17日至19日在宾夕法尼亚州匹兹堡举行的第七届活脑功能神经受体映射国际研讨会（NRM 08）。该研讨会是学术界和制药业杰出科学家和医生的两年一度的会议，他们的努力集中在非侵入性成像技术的发展上，如正电子发射断层扫描（PET）和单光子发射计算机断层扫描（SPECT），以功能表征和量化神经受体群体（例如5-羟色胺-2A、多巴胺D2）和受体样蛋白（例如脑淀粉样蛋白）。该小组的首要目标是将非侵入性成像方法应用于：1）提高对神经退行性疾病和精神障碍、成瘾和正常衰老的病理生理学的理解; 2）开发体内定量神经受体功能的改进方法; 3）有效地使用神经受体成像技术来加速中枢神经系统（CNS）药物开发的过程;以及4）使用神经受体成像来监测新型CNS药物在患者中的疗效。会议的科学计划将侧重于与NIMH和NIDA赞助的研究直接相关的基础和临床研究。专题讨论会方案的主要组成部分将包括约30个平台介绍和150个与会者提交会议的摘要海报介绍。该计划还将包括两个主题讲座，突出两个或更多会议主题的专题讲座，关键问题的小组讨论和网络活动。本次研讨会将利用在功能性神经影像领域工作的真正多学科和国际科学家和医生观众的专业知识广度，以促进对疾病病理生理学的理解，开发改进的技术和方法，确定和探索可能推进临床诊断和药物开发的转化研究机会，并建立和促进沟通，合作，和这群功能成像专家之间的友谊。第七届活脑功能性神经受体映射国际研讨会（NRM 08）将利用在功能性神经成像领域工作的真正多学科和国际科学家和医生的专业知识，以促进对疾病病理生理学的理解，开发改进的成像技术和方法，识别和探索可能促进临床诊断和药物开发的转化研究机会，并建立和促进这组功能成像专家之间的沟通，合作和研究。本次会议的整体效益是实现本地，国家和国际，因为这个论坛支持集中在科学问题上，可以显着影响研究发展在这个强大的和充满活力的多模态神经影像学研究社区，产生新的临床和技术研究成果，并支持国家的最先进的教育机会，为研究生，医学生，以及多模态成像技术的教师。

DESCRIPTION (provided by applicant): We seek $49,000 in support from NIMH and NIDA to host the Seventh International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM08) from July 17-19, 2008, in Pittsburgh, PA. This symposium is a biennial meeting of preeminent scientists and physicians in academia and the pharmaceutical industry whose efforts focus on the development of non-invasive imaging techniques, such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT), to functionally characterize and quantify populations of neuroreceptors (e.g. serotonin-2A, dopamine D2) and receptor-like proteins (e.g. brain amyloid) in the living human brain. The overarching goals of this group are to apply non- invasive imaging methods to: 1) improve the understanding of the pathophysiology of neurodegenerative diseases and psychiatric disorders, addiction, and normal aging; 2) to develop improved methods of quantifying neuroreceptor function in vivo; 3) to effectively use neuroreceptor imaging techniques to accelerate the process of central nervous system (CNS) drug development; and 4) to use neuroreceptor imaging to monitor the efficacy of novel CNS drugs in patients. The scientific program for the meeting will focus on basic and clinical research that is of direct relevance to NIMH and NIDA sponsored research. The main component of the symposium program will include approximately 30 platform presentations and 150 poster presentations of abstracts submitted to the meeting from meeting participants. The program will also include two keynote lectures, thematic lectures that highlight two or more conference themes, panel discussions of key issues, and networking events. This symposium will leverage the breadth of expertise of a truly multidisciplinary and international audience of scientists and physicians working in the area of functional neuroimaging to advance the understanding of the pathophysiology of disease, develop improved techniques and methods, identify and explore translational research opportunities that may advance clinical diagnostics and drug development, and to establish and foster communication, collaboration, and fellowship among this group of functional imaging experts. The Seventh International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM08) will leverage the breadth of expertise of a truly multidisciplinary and international audience of scientists and physicians working in the area of functional neuroimaging to advance the understanding of the pathophysiology of disease, develop improved imaging techniques and methods, identify and explore translational research opportunities that may advance clinical diagnostics and drug development, and to establish and foster communication, collaboration, and fellowship among this group of functional imaging experts. The overall benefit of this meeting is realized locally, nationally, and internationally, as this forum supports focused concentration on scientific issues that can significantly impact research developments within this strong and vibrant multimodality neuroimaging research community, yield novel clinical and technical research findings, and support state-of-the-art educational opportunities for graduate students, medical students, and faculty in multimodality imaging techniques.