Identification and characterization of a novel tumor suppressor
新型肿瘤抑制因子的鉴定和表征
基本信息
- 批准号:nhmrc : 628365
- 负责人:
- 金额:$ 39.47万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:NHMRC Project Grants
- 财政年份:2010
- 资助国家:澳大利亚
- 起止时间:2010-01-01 至 2012-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Australia has the highest rate of skin cancer in the world, with over 380,000 people diagnosed every year. Of these, over 370,000 have non-melanoma skin cancers including squamous cell carcinoma and basal cell carcinoma. Our laboratory has identified a gene in mice that protects animals from squamous cell cancer. The studies proposed in this grant examine the mechanisms underpinning this protective role and may have important implications for the prevention of skin cancers in humans.
澳大利亚是世界上皮肤癌发病率最高的国家,每年有超过38万人被诊断出皮肤癌。其中,超过37万人患有非黑色素瘤皮肤癌,包括鳞状细胞癌和基底细胞癌。我们的实验室已经在小鼠中发现了一种保护动物免受鳞状细胞癌的基因。这项资助中提出的研究检查了支持这种保护作用的机制,可能对预防人类皮肤癌具有重要意义。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Prof John Cunningham其他文献
Prof John Cunningham的其他文献
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{{ truncateString('Prof John Cunningham', 18)}}的其他基金
Defects in epidermal morphogenesis in Grainyhead-like gene deficient mice
粒头样基因缺陷小鼠表皮形态发生缺陷
- 批准号:
nhmrc : 544304 - 财政年份:2009
- 资助金额:
$ 39.47万 - 项目类别:
NHMRC Project Grants
Analysis of factors governing globin gene expression
珠蛋白基因表达的影响因素分析
- 批准号:
nhmrc : 489411 - 财政年份:2008
- 资助金额:
$ 39.47万 - 项目类别:
NHMRC Project Grants
Defects in epidermal morphogenesis in mammalian Grainyhead-like gene deficient mice
哺乳动物粒头样基因缺陷小鼠表皮形态发生缺陷
- 批准号:
nhmrc : 382903 - 财政年份:2006
- 资助金额:
$ 39.47万 - 项目类别:
NHMRC Project Grants
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