DEVELOPMENT CONSEQUENCES OF INFANT ABUSE IN PRIMATES

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project investigates the behavioral and neuroendocrine development of rhesus macaque infants who are abused by their mothers and their nonabused controls. In this year of the project, we analyzed and published some of our data documenting the early social experience of abused and nonabused infants, the differences in the infants' CSF monoamine metabolite levels in relation to genotype and early experience, and the role of the serotonergic system in the intergenerational transmission of maternal rejection and infant abuse among rhesus macaque females.