SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER

支持国家灵长类研究中心

• 批准号: 7479428
• 负责人: JOSEPH E ROBERTSON
• 金额: $ 95.48万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7479428
• 关键词: Area; Assisted Reproductive Technology; Behavioral; Biology of Aging; Biomedical Research; Breeding; Businesses; Cellular biology; Clinical Medicine; Communicable Diseases; Development; Developmental Biology; Endocrine; Engineering; Environmental Health; Equipment; Funding; Genetic; Grant; Health Services Research; Imaging technology; Immunology; Information Technology; Interdisciplinary Study; Laboratory Animals; Libraries; Macaca mulatta; Magnetic Resonance Imaging; Metabolic Diseases; Modeling; Modernization; Molecular and Cellular Biology; Morphology; Neurosciences; Obesity; Office of the Director; Operative Surgical Procedures; Pathology; Pilot Projects; Primates; Property; Radiation; Reproductive Immunology; Research; Research Infrastructure; Research Support; Resources; Safety; Science; Serologic tests; Services; Stem cells; Study of serum; Women' s Health; Work; animal resource; human disease; nonhuman primate; programs; vaccine development; virology

The 5-year renewal for Grant P51 RR00163-50 requests funding for programs at the ONPRC that support biomedical research. The application reflects a new strategic focus on interdisciplinary research to optimize the use and development of nonhuman primate (NHP) models. The aims of this application are to: 1) provide the infrastructure support necessary to conduct advanced biomedical research for which NHPs are used to accelerate progress in understanding human diseases; 2) enhance the Center's resources (scientific expertise, laboratories, animal services, research support cores and equipment) so as to serve as a regional and national resource; 3) increase the availability of defined NHPs for biomedical research through support of our programs to expand the SPF Indian-origin rhesus macaque breeding program; and 4) expand research programs utilizing NHPs in stem cell biology, aging, obesity, genetics, infectious diseases, vaccine development, neuroscience and women's health. To accomplish these aims, support is requested in three broad areas. First, Administration & Center Operations provide the administrative and service support required for all aspects of the ONPRC. Units include: 1) the Director's Office; 2) Administrative Services (Business Services, Environmental Health & Radiation Safety, Facilities & Property, Information Technology & Engineering, and the Research Library); 3) Animal Resources (Administration, Operations, Behavioral Services, Pathology Services, Surgery Services, and Clinical Medicine); and 4) Research Support Cores (Assisted Reproductive Technology, Endocrine Technology, Imaging & Morphology, Immunology, Magnetic Resonance Imaging, Molecular & Cellular Biology, and Virology & Serology). Secondy, Scientific Components include support for: 1) Scientific Divisions (Neuroscience, Pathobiology & Immunology, and Reproductive Sciences) and their interdisciplinary Working Groups (Biology of Aging, Metabolic Disease, and Stem Cell & Developmental Biology); 2) the Collaborative Research Unit that facilitates externallyfunded research; 3) the Pilot Project Program; and 4) Resource-Related Research. Finally, Improvement & Modernization includes funds for equipment and alterations and renovations.

赠款 P51 RR00163-50 的 5 年续展请求为 ONPRC 的项目提供资金，这些项目支持 生物医学研究。该申请体现了跨学科研究的新战略重点，以优化 非人类灵长类动物（NHP）模型的使用和开发。该应用程序的目的是：1）提供 进行先进生物医学研究所需的基础设施支持，其中 NHP 用于 加速了解人类疾病的进展； 2）增强中心的资源（科学 专业知识、实验室、动物服务、研究支持核心和设备），从而充当区域性 和国家资源； 3) 通过支持增加用于生物医学研究的特定 NHP 的可用性 我们扩大 SPF 印度原产恒河猴育种计划的计划； 4) 扩展 利用 NHP 进行干细胞生物学、衰老、肥胖、遗传学、传染病、疫苗等领域的研究项目 发展、神经科学和妇女健康。为了实现这些目标，需要在三个方面提供支持 广阔的领域。首先，行政和中心运营提供行政和服务支持 ONPRC 各个方面都需要。单位包括： 1）主任办公室； 2) 行政服务 （商业服务、环境健康与辐射安全、设施与财产、信息技术 与工程和研究图书馆）； 3) 动物资源（管理、操作、行为 服务、病理学服务、手术服务和临床医学）； 4) 研究支持核心 （辅助生殖技术、内分泌技术、影像与形态学、免疫学、磁学 共振成像、分子和细胞生物学以及病毒学和血清学）。第二，科学 组成部分包括对以下方面的支持：1) 科学部门（神经科学、病理生物学和免疫学，以及 生殖科学）及其跨学科工作组（衰老生物学、代谢疾病、 和干细胞与发育生物学）； 2）促进外部资助的合作研究单位 研究; 3) 试点项目计划； 4) 资源相关研究。最后，改进& 现代化包括设备、改建和翻新资金。