SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER

赠款P51 RR 00163 -50的5年续期要求为ONPRC的项目提供资金， 生物医学研究该申请反映了跨学科研究的新战略重点，以优化 非人灵长类动物（NHP）模型的使用和发展。本申请的目的是：1）提供 进行先进的生物医学研究所需的基础设施支持，NHP用于 加快人类疾病的认识; 2）加强中心的资源（科学 专业知识，实验室，动物服务，研究支持核心和设备），以作为一个区域 3）通过支持， 我们的计划，以扩大SPF印度起源恒河猴繁殖计划;和4）扩大 在干细胞生物学、衰老、肥胖、遗传学、传染病、疫苗中利用NHP的研究计划 发展、神经科学和妇女健康。为了实现这些目标，需要在三个方面提供支助。 广阔的领域。首先，行政和中心运营提供行政和服务支持 这是ONPRC所有方面所需的。单位包括：1）主任办公室; 2）行政事务处 （商业服务、环境健康与辐射安全、设施与财产、信息技术 3）动物资源（管理、运营、行为学和生物学） 服务、病理学服务、外科服务和临床医学）;以及4）研究支持核心 （辅助生殖技术，内分泌技术，成像和形态学，免疫学，磁 共振成像、分子和细胞生物学以及病毒学和血清学）。Secondy，Scientific 组成部分包括支持：1）科学部门（神经科学，病理生物学和免疫学， 生殖科学）及其跨学科工作组（衰老生物学，代谢疾病， 和干细胞与发育生物学）; 2）促进外部资助的合作研究单位 研究; 3）试点项目计划;和4）资源相关的研究。最后，改善& 现代化包括设备、改建和翻修的资金。

The 5-year renewal for Grant P51 RR00163-50 requests funding for programs at the ONPRC that support biomedical research. The application reflects a new strategic focus on interdisciplinary research to optimize the use and development of nonhuman primate (NHP) models. The aims of this application are to: 1) provide the infrastructure support necessary to conduct advanced biomedical research for which NHPs are used to accelerate progress in understanding human diseases; 2) enhance the Center's resources (scientific expertise, laboratories, animal services, research support cores and equipment) so as to serve as a regional and national resource; 3) increase the availability of defined NHPs for biomedical research through support of our programs to expand the SPF Indian-origin rhesus macaque breeding program; and 4) expand research programs utilizing NHPs in stem cell biology, aging, obesity, genetics, infectious diseases, vaccine development, neuroscience and women's health. To accomplish these aims, support is requested in three broad areas. First, Administration & Center Operations provide the administrative and service support required for all aspects of the ONPRC. Units include: 1) the Director's Office; 2) Administrative Services (Business Services, Environmental Health & Radiation Safety, Facilities & Property, Information Technology & Engineering, and the Research Library); 3) Animal Resources (Administration, Operations, Behavioral Services, Pathology Services, Surgery Services, and Clinical Medicine); and 4) Research Support Cores (Assisted Reproductive Technology, Endocrine Technology, Imaging & Morphology, Immunology, Magnetic Resonance Imaging, Molecular & Cellular Biology, and Virology & Serology). Secondy, Scientific Components include support for: 1) Scientific Divisions (Neuroscience, Pathobiology & Immunology, and Reproductive Sciences) and their interdisciplinary Working Groups (Biology of Aging, Metabolic Disease, and Stem Cell & Developmental Biology); 2) the Collaborative Research Unit that facilitates externallyfunded research; 3) the Pilot Project Program; and 4) Resource-Related Research. Finally, Improvement & Modernization includes funds for equipment and alterations and renovations.