ESTABLISHMENT OF A SPF RHESUS MACAQUE COLONY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目的目标是提高国家生产无疱疹B病毒、SIV、SRV和STLV-1特异性病原体（SPF）的印度恒河猴（Macaca mulatta）的能力。 殖民地将继续生产高质量的具有遗传特征的动物，用于美国国立卫生研究院西南国家灵长类动物研究中心（SNPRC）和美国西南地区其他研究机构的艾滋病相关研究。 SNPRC殖民地的大部分原始种群是通过从美国空军（USAF）收购现有的SPF殖民地获得的。 向SNPRC提供了C 06赠款（RR-01-130，SNPRC SPF恒河猴设施），用于建造新住房。 拟定的生产和收购计划将增加殖民地规模，以达到430只动物的稳定状态。 这一目标群体规模将允许从06年开始每年收获70只动物，以满足艾滋病相关研究的关键需求和美国空军的研究需求。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this project is to increase the nation's capacity to produce Indian-origin rhesus monkeys (Macaca mulatta) that are specific pathogen-free (SPF) for herpes B virus, SIV, SRV, and STLV-1. The colony will continue to produce high quality genetically characterized animals for use I AIDS-related research by NIH grantees based at the Southwest National Primate Research Center (SNPRC) and at other research institutions in the southwestern region of the United States. Most of the founding stock of the SNPRC colony was obtained through acquisition of an existing SPF colony from the U.S. Air Force (USAF) to the Primate Center. A C06 grant (RR-01-130, SPF Rhesus Macaque Facility for SNPRC) was awarded to the SNPRC for the construction of new housing. The proposed production and acquisition schedule will result in increasing the colony size to achieve a steady state of 430 animals. This target colony size will allow an annual harvesting of 70 animals per year beginning in Year 06 to fulfill critical needs in AIDS-related research and research needs of the USAF.