ESTABLISHMENT OF A SPF RHESUS MACAQUE COLONY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的目标是提高印度的能力，培育出对B型疱疹病毒、SIV、SRV和STLV-1无特定病原体(SPF)的印度源恒河猴(Macaca Mulatta)。该殖民地将继续生产高质量的具有基因特征的动物，供设在西南国家灵长类动物研究中心(SNPRC)和美国西南部地区其他研究机构的NIH受资助者进行与艾滋病相关的研究。SNPRC殖民地的大部分创始股票是通过从美国空军(USAF)向灵长类中心收购一个现有的SPF殖民地获得的。向SNPRC发放了C06赠款(RR-01-130，SPF恒河猴设施，用于建造新住房)。拟议的生产和收购计划将导致增加群体规模，以达到430只动物的稳定状态。这一目标群体规模将允许从06年开始每年收获70只动物，以满足艾滋病相关研究的关键需求和美国空军的研究需求。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this project is to increase the nation's capacity to produce Indian-origin rhesus monkeys (Macaca mulatta) that are specific pathogen-free (SPF) for herpes B virus, SIV, SRV, and STLV-1. The colony will continue to produce high quality genetically characterized animals for use I AIDS-related research by NIH grantees based at the Southwest National Primate Research Center (SNPRC) and at other research institutions in the southwestern region of the United States. Most of the founding stock of the SNPRC colony was obtained through acquisition of an existing SPF colony from the U.S. Air Force (USAF) to the Primate Center. A C06 grant (RR-01-130, SPF Rhesus Macaque Facility for SNPRC) was awarded to the SNPRC for the construction of new housing. The proposed production and acquisition schedule will result in increasing the colony size to achieve a steady state of 430 animals. This target colony size will allow an annual harvesting of 70 animals per year beginning in Year 06 to fulfill critical needs in AIDS-related research and research needs of the USAF.