Cellular Basis of Immunological and Neurological Disease

免疫和神经疾病的细胞基础

• 批准号: 7471544
• 负责人: Eric Holmes
• 金额: $ 232.08万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7471544
• 关键词: Cellular; Basis; Immunological; Neurological; Disease

DESCRIPTION (provided by applicant): Building upon the network foundation established by BRIN, INBRE proposes to expand and to develop Hawaii's competitive biomedical research capacity. The expansion will center on three thematic projects exploring the cellular basis of immunological and neurological diseases from the perspective of immunology, cell biology, and developmental biology. Each project will be led by a well-established senior investigator who will mentor junior investigators at both the lead and the affiliated baccalaureate institutions. This will extend into the state's community colleges where participating faculty will collaborate with established researchers at the lead institution. Each investigator - senior, junior, and Outreach - will recruit and mentor undergraduate and graduate students as well. The development will concentrate on not only individual research careers but also the network's overall approach to competitive research. This involves the establishment of rigorous standards and performance expectations coupled with attentive mentoring to assist network investigators and students in meeting these challenging criteria. Organizationally, INBRE will consist of four major cores: Administrative, Research, Bioinformatics, and Outreach. The Administrative Core will provide overall administrative support, including maintenance of the network's web site, evaluation efforts, and training and mentoring workshops and seminars. The Research Core will be comprised of the three thematic research projects with a Core leader to ensure project coordination. The Outreach Core extends the research thrust into the community colleges by promoting research and student participation through collaborations with the lead and the baccalaureate institutions. The Bioinformatics Core will also provide unique opportunities by emphasizing academic work force development. To facilitate this, the Core will be housed within the University of Hawaii at Manoa's Department of Information and Computer Sciences.

描述（由申请人提供）：在 BRIN 建立的网络基础上，INBRE 提议扩大和发展夏威夷具有竞争力的生物医学研究能力。此次扩展将围绕三个主题项目，从免疫学、细胞生物学和发育生物学的角度探索免疫和神经疾病的细胞基础。每个项目都将由一位经验丰富的高级研究员领导，他将指导牵头机构和附属学士学位机构的初级研究员。这将扩展到该州的社区学院，参与的教师将与牵头机构的知名研究人员合作。每位研究者——高级、初级​​和外展——也将招募和指导本科生和研究生。发展不仅将集中于个人研究事业，还将集中于网络竞争性研究的整体方法。这涉及建立严格的标准和绩效期望，以及细心的指导，以帮助网络调查人员和学生满足这些具有挑战性的标准。在组织上，INBRE 将 由四个主要核心组成：行政、研究、生物信息学和外展。行政部门 核心将提供全面的行政支持，包括网络网站的维护、评估工作以及培训和指导讲习班和研讨会。研究核心将由三个专题研究项目组成，并由一名核心领导者确保项目协调。外展核心通过与领先机构和学士学位机构合作促进研究和学生参与，将研究主力扩展到社区学院。生物信息学核心还将通过强调学术劳动力的发展来提供独特的机会。为了实现这一目标，该核心将设在夏威夷大学马诺阿分校信息与计算机科学系内。